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Postion:Product Catalog >7-Chlorokynurenic acid
7-Chlorokynurenic acid
  • 7-Chlorokynurenic acid

7-Chlorokynurenic acid NEW

Price $38 $61 $128
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-11

Product Details

Product Name: 7-Chlorokynurenic acid CAS No.: 18000-24-3
Purity: 99.72% Supply Ability: 10g
Release date: 2024/11/11

Product Introduction

Bioactivity

名稱7-Chlorokynurenic acid
描述7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) is an effecitve and selective antagonist of NMDA receptor with IC50 of 0.56 μM for the glycine B coagonist site. 7-Chlorokynurenic acid inhibits the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM and shows antinociceptive actions after neuraxial delivery.
體內(nèi)活性In male Sprague-Dawley rats, 7-Chlorokynurenic acid (10 nM) retardates the development of both the electroencephalographic and motor (17.7 daily stimulations) components of the seizure response[3].
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 15 mg/mL (67.1 mM), Sonication is recommended.
關(guān)鍵字7-Chlorokynurenic acid
相關(guān)庫海洋天然產(chǎn)物庫 | 疼痛相關(guān)化合物庫 | 神經(jīng)退行性疾病化合物庫 | 經(jīng)典已知活性庫 | 天然產(chǎn)物庫 | 微生物天然產(chǎn)物庫 | 抑制劑庫 | 神經(jīng)保護化合物庫 | 高通量篩選天然產(chǎn)物庫 | 已知活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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