7-Azaindole NEW
| Price | Get Latest Price |
| Package | 25KG |
| Min. Order: | 1KG |
| Supply Ability: | 50000KG/month |
| Update Time: | 2023-09-01 |
Product Details
| Product Name: 7-Azaindole | CAS No.: 271-63-6 |
| EC-No.: 205-981-0 | Min. Order: 1KG |
| Purity: 99% | Supply Ability: 50000KG/month |
| Release date: 2023/09/01 |
| CAS: | 271-63-6 |
| MF: | C7H6N2 |
| MW: | 118.14 |
| EINECS: | 205-981-0 |
| Product Categories: | blocks;IndolesOxindoles;Heterocycles;Heterocycles series;Indole Derivatives;Pharmaceutical intermediate;Indole;Heterocyclic Compounds;Indole Series;Aromatics;Heterocycle-Indole series;Heterocycle-Pyridine series;buildingblock;Halogenated Heterocycles ,Thiazoles;Intermediates & Fine Chemicals;Pharmaceuticals |
| Mol File: | 271-63-6.mol |
 | |
| 7-Azaindole Chemical Properties |
| Melting point | 105-107 °C (lit.) |
| Boiling point | 270 °C (753.1004 mmHg) |
| density | 1.1151 (rough estimate) |
| refractive index | 1.5500 (estimate) |
| Fp | 270°C |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform, Methanol |
| pka | 7.69±0.20(Predicted) |
| form | Powder |
| color | White to off-white |
| BRN | 109667 |
| InChIKey | MVXVYAKCVDQRLW-UHFFFAOYSA-N |
| CAS DataBase Reference | 271-63-6(CAS DataBase Reference) |
| NIST Chemistry Reference | 1H-Pyrrolo[2,3-b]pyridine(271-63-6) |
| EPA Substance Registry System | 1H-Pyrrolo[2,3-b]pyridine (271-63-6) |
| 7-Azaindole Usage And Synthesis |
| Chemical Properties | Brown-Cyrstalline Solid |
| Uses | 7-Azaindole is imidazolinone derivatives as CGRP receptor antagonists used in the treatment. A heterocyclic molecule that can be utilized as a pharmaceutical building block. Starting material in a recent synthesis of azaserotonin. |
| Application | 7-Azaindole is a heterocyclic organic compound, which is an organic synthesis intermediate and a pharmaceutical intermediate. It is the core structure of many drugs, such as antitumor drugs, dopamine D4 receptors, p38 kinase inhibitors, thrombin inhibitors, etc. |
| Preparation | Synthesis of 7-azaindole: in a single-necked flask, add 2.0 g of 2-amino-3-methylpyridine and 2.5 g of N-Methylformanilide into 40 mL of dichloromethane, and add 3.15 g of PCl with stirring under an ice-water bath. After 4 hours of reaction, the reaction system was slowly poured into 40 mL of ammonia water, and the insoluble matter was removed by suction filtration. The organic layer was separated, washed twice with water, dried over anhydrous sodium sulfate, and evaporated to dryness to obtain 2.91 g of 7-azaindole as a pale yellow solid, with a yield of 70%. |
| Definition | ChEBI: 1H-pyrrolo[2,3-b]pyridine is a pyrrolopyridine. |
| Purification Methods | Recrystallise it repeatedly from EtOH, then sublime it in a vacuum [Tokumura et al. J Am Chem Soc 109 1346 1987]. The N-acetate has m 65-66o (from *C6H6), and the picrate has m 232-233o (from Me2CO) [Clemo & Swan J Chem Soc 603 1945, Beilstein 23 III/IV 1105.] |
Packing &shipping&Payment
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
Advantage
In stock
Company Profile Introduction
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $9.85/1KG |
VIP6Y
|
Hebei Weibang Biotechnology Co., Ltd
|
2024-11-05 | |
| $9.00/1KG |
VIP4Y
|
Hebei Chuanghai Biotechnology Co,.LTD
|
2024-08-21 | |
| $30.00/1kg |
VIP1Y
|
hebei hongtan Biotechnology Co., Ltd
|
2024-05-14 | |
| $8.00/1KG |
VIP1Y
|
Henan Fengda Chemical Co., Ltd
|
2024-01-22 | |
| $0.00/1KG |
VIP3Y
|
Henan Aochuang Chemical Co.,Ltd.
|
2022-10-13 | |
| $375.00/1kg |
BTC pharm India
|
2022-07-22 | ||
| $2.00/25KG |
VIP6Y
|
Jinan Finer Chemical Co., Ltd
|
2022-04-28 | |
| $15.00/1KG |
Zhuozhou Wenxi import and Export Co., Ltd
|
2021-07-10 | ||
| $100.00/1g |
VIP5Y
|
Shaanxi Dideu Medichem Co. Ltd
|
2019-12-31 | |
| $1.00/1kg |
VIP7Y
|
Career Henan Chemical Co
|
2018-12-20 |
Japan
- Since: 2017-12-08
- Address: Building A, Enjoy city, Zhongshan East Road, Shijiazhuang city, Hebei province
13288715578
sales@hbmojin.com