Ridaforolimus
Price | $7 |
Package | 1KG |
Min. Order: | 1KG |
Supply Ability: | JD 427 |
Update Time: | 2019-09-02 |
Product Details
Product Name: Ridaforolimus | CAS No.: 572924-54-0 |
Min. Order: 1KG | Purity: 99% |
Supply Ability: JD 427 | Release date: 2019/09/02 |
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Product Name:
Ridaforolimus
Synonyms:
AP 23573, MK 8669, 42-DiMethylphosphinate-rapaMycin;RapaMycin,42-(diMethylphosphinate) (9CI);deforolimus 572924-54-0;572924-54-0;Deforolimus (AP23573)42-;Deforolimus, 98%, a potent and selective mTOR inhibitor;42-(Dimethylphosphinate)rapamycin;Deforolimus
CAS:
572924-54-0
MF:
C53H84NO14P
MW:
990.214
EINECS:
Product Categories:
Inhibitors;Akt;Intermediates & Fine Chemicals;Pharmaceuticals;mTOR;PI3K
Mol File:
572924-54-0.mol
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Ridaforolimus Chemical Properties
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Melting point
95-98°C
storage temp.
Hygroscopic, -20?C Freezer, Under Inert Atmosphere
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Safety Information
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MSDS Information
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Ridaforolimus Usage And Synthesis
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Chemical Properties
Off-White Solid
Uses
An immunosupressant and is currently being investigated for use in cancer treatments. Ridaforolimus may act as a regulator of protein synthesis, cell proliferation, cell cycle progression and cell survival. Ridaforolimus, was formerly known as Deforolimus.
Uses
Ridaforolimus is a semisynthetic macrocyclic lactone prepared from rapamycin by selective alkylation of the 42-hydroxy group with a dimethylphosphinate moiety. Like all tacrolimus analogues, ridaforolimus binds to receptor protein, FKBP12. The complex then binds to mTOR preventing its interaction with target proteins. Ridaforolimus is extensively cited in the literature with over 70 citations.
Definition
ChEBI: A semisynthetic derivative that is sirolimus in which hydroxy group attached to the cyclohexyl moiety has been converted to the corresponding dimethylphosphinate.
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates:
Pharmaceutical intermediates;
OLED intermediates;
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Recommended supplier
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$50.00/20mg |
NanJing Spring & Autumn Biological Engineering CO., LTD.
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2019-07-17 |
- Since: 2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
INQUIRY
楊俊青
sales@coreychem.com
sales@coreychem.com