BUCILLAMINE
Price | $1 |
Package | 1KG |
Min. Order: | 1KG |
Supply Ability: | 200kg |
Update Time: | 2019-09-02 |
Product Details
Product Name: BUCILLAMINE | CAS No.: 65002-17-7 |
Min. Order: 1KG | Purity: 98% |
Supply Ability: 200kg | Release date: 2019/09/02 |
Product No:: Cindy 12 |
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Product Name:
BUCILLAMINE
Synonyms:
n-(2-mercapto-2-methyl-1-oxopropyl)-l-cystein;n-(2-mercapto-2-methyl-1-oxopropyl)-l-cysteine;n-(2-mercapto-2-methylpropanoyl)-l-cysteine;n-(2-mercapto-2-methylpropionyl)-l-cysteine;n-(2-mercaptoisobutyryl)-l-cysteine;rimatil;sa96;thiobutarit
CAS:
65002-17-7
MF:
C7H13NO3S2
MW:
223.31
EINECS:
Product Categories:
-;Amino Acids & Derivatives;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:
65002-17-7.mol
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BUCILLAMINE Chemical Properties
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Melting point
119-123°C
alpha
D25 +32.3° (c = 1.0 in ethanol)
density
1.3934 (rough estimate)
refractive index
1.6370 (estimate)
storage temp.
Hygroscopic, -20?C Freezer, Under Inert Atmosphere
CAS DataBase Reference
65002-17-7(CAS DataBase Reference)
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Safety Information
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Toxicity
LD50 in mice (mg/kg): 2285 i.p.; 989.6 i.v. (Fujita, 1981)
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MSDS Information
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BUCILLAMINE Usage And Synthesis
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Description
Bucillamine is an orally active immunomodulator useful in the treatment of rheumatoid arthritis. Its potencies in inhibiting collagenase activity and inactivating rheumatoid factor far exceed those of penicillamine. In man, bucillamine reportedly brings about significant improvements over placebo in erythrocyte sedimentation, grip power, joint swelling and duration of morning stiffness.
Chemical Properties
Off-White Solid
Originator
Santen (Japan)
Uses
An antirheumatic agent.
Brand name
Rimatil
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BUCILLAMINE Preparation Products And Raw materials
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Raw materials
Thionyl chloride-->Ammonia-->Ammonium chloride -->Silica gel-->Phenylacetic acid ethyl ester-->Isobutyryl chloride-->2-MERCAPTOISOBUTYRIC ACID-->S-Benzyl-L-cysteine
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Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates:
Pharmaceutical intermediates;
OLED intermediates;
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- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
INQUIRY
楊俊青
sales@coreychem.com
sales@coreychem.com