5,6-DIHYDROXYINDOLE NEW
| Price | $35 | $1.4 |
| Package | 1kg | 1000kg |
| Min. Order: | 1kg |
| Supply Ability: | g-kg-tons, free sample is available |
| Update Time: | 2024-04-02 |
Product Details
| Product Name: 5,6-DIHYDROXYINDOLE | CAS No.: 3131-52-0 |
| Min. Order: 1kg | Purity: 99% |
| Supply Ability: g-kg-tons, free sample is available | Release date: 2024/04/02 |
| Lead time: In stock, ready for shipment | In stock, ready for shipment: bag/bottle/drum/IBC |
| bag/bottle/drum/IBC: By express, by air, by sea | Origin: Manufacturer, advantage product |
| COA, MSDS: Available, contact us for details | Name: Mia |
1. Materials information
| Name | 5,6-dihydroxyindole |
|---|---|
| Synonym | More Synonyms |
| Description | 5,6-Dihydroxyindole, a melanin precursor, has a broad-spectrum antibacterial, antifungal, antiviral, antiparasitic activity. 5,6-Dihydroxyindole has cytotoxic effects and is strongly toxic against various pathogens[1]. |
|---|---|
| Related Catalog | Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial |
| Target | Human Endogenous Metabolite |
| In Vitro | 5,6-Dihydroxyindole (1, 10, 20, 50, 100 μM; for 4 hours) dose-dependently decreases OD492 values. Pretreatment of Sf9 cells with 1.0 mM 5,6-Dihydroxyindole for 4 hours results in 97% mortality, and LC50 values of 20.3 μM in buffer and 131.8 μM in a culture medium[1]. Preincubation of a baculovirus stock with 1.25 mM 5,6-Dihydroxyindole for 3 hours near fully disables recombinant protein production. The LC50 for lambda bacteriophage and eggs of the wasp Microplitis demolitor are 5.6 and 111.0 μM, respectively[1]. 5,6-Dihydroxyindole and its spontaneous oxidation products are also active against viruses and parasitic wasps[1]. |
| References | [1]. Zhao P, et al. Antiviral, anti-parasitic, and cytotoxic effects of 5,6-dihydroxyindole (DHI), a reactive compound generated by phenoloxidase during insect immune response. Insect Biochem Mol Biol. 2011 Sep;41(9):645-52. [2]. Heiduschka P, et al. Melanin precursor 5,6-dihydroxyindol: protective effects and cytotoxicity on retinal cells in vitroand in vivo. Toxicol Pathol. 2007 Dec;35(7):1030-8. |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 411.2±25.0 °C at 760 mmHg |
| Molecular Formula | C8H7NO2 |
| Molecular Weight | 149.147 |
| Flash Point | 202.5±23.2 °C |
| Exact Mass | 149.047684 |
| PSA | 56.25000 |
| LogP | 0.37 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.802 |
| Storage condition | 2-8°C |
2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
By Express
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
By Air
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
By Sea
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
4. Contact information
For more details, pls contact us freely.
Email address: mia@fdachem.com
Mob: 86 18336764634
WhatsApp/Skype/Wechat/LINE: 86 18336764634
Company Profile Introduction
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $1.00/200KG |
VIP6Y
|
Hebei Weibang Biotechnology Co., Ltd
|
2024-11-01 | |
| $0.00/25KG |
VIP3Y
|
Hebei Weibang Biotechnology Co., Ltd
|
2024-10-31 | |
| $6.00/1kg |
VIP2Y
|
Jinan Million Pharmaceutical Co., Ltd
|
2024-09-25 | |
| $1.00/1kg |
VIP6Y
|
Zhengzhou HQ Material CO.,LTD.
|
2024-08-22 | |
| $0.00/10mg |
VIP1Y
|
ShenZhen H&D Pharmaceutical Technology Co., LTD
|
2024-07-11 | |
| $1.00/1KG |
VIP6Y
|
Shaanxi Dideu Medichem Co. Ltd
|
2024-07-07 | |
| $180.00/1kg |
VIP1Y
|
Hebei Zhuanglai Chemical Trading Co.,Ltd
|
2024-06-06 | |
| $5400.00/1KG |
VIP1Y
|
Hubei Yiling biotechnology Co Ltd
|
2024-05-14 | |
| $15.00/1kg |
Ouhuang Engineering Materials (Hubei) Co., Ltd
|
2024-04-26 | ||
| $0.00/1g |
VIP1Y
|
airuikechemical co., ltd.
|
2024-04-07 |
China
- Since: 2023-02-10
- Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro