5-Chloro-2-nitroaniline NEW
| Price | $100 | $1 |
| Package | 1KG | 1000KG |
| Min. Order: | 1KG |
| Supply Ability: | g-kg-tons, free sample is available |
| Update Time: | 2023-12-24 |
Product Details
| Product Name: 5-Chloro-2-nitroaniline | CAS No.: 1635-61-6 |
| Min. Order: 1KG | Purity: 99% |
| Supply Ability: g-kg-tons, free sample is available | Release date: 2023/12/24 |
| Lead time: In stock | Packaging: bottle/ drum/ bucket/ IBC, as request. |
| Delivery: By sea, by air, by express | Origin: Manufacturer |
1. Product information
| Product Name: | 5-Chloro-2-nitroaniline |
| Synonyms: | TIMTEC-BB SBB003828;2-AMINO-4-CHLORO-NITROBENZENE;5-CHLORO-2-NITROANILINE;5-CHLORO-2-NITROBENZENAMINE;5-chloro-2-nitro-benzenamin;Benzenamine, 5-chloro-2-nitro-;2-NITRO-5-CHLOROANILINE;2-Amino-4-chloro-1-nitrobenzene |
| CAS: | 1635-61-6 |
| MF: | C6H5ClN2O2 |
| MW: | 172.57 |
| EINECS: | 216-661-5 |
| Product Categories: | Pyrimidines;API intermediates |
| Mol File: | 1635-61-6.mol |
 | |
| 5-Chloro-2-nitroaniline Chemical Properties |
| Melting point | 125-129 °C (dec.)(lit.) |
| Boiling point | 200°C (rough estimate) |
| density | 1.5610 (rough estimate) |
| refractive index | 1.5870 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | soluble in Chloroform, Methanol |
| form | Liquid |
| pka | -1.46±0.25(Predicted) |
| color | Clear colorless to light yellow |
| 5-Chloro-2-nitroaniline Usage And Synthesis |
| Description | 2-Nitro-5-chloroaniline is an important pharmaceutical and veterinary drug intermediate. It has been applied in the upgraded product of veterinary drug albendazole-fenbendazole, and has a broad market prospect. |
| Preparation | Add 2.46mol of 2,4-dichloronitrobenzene, 7.72mol of toluene to a 3L autoclave, seal the autoclave, replace the air with nitrogen, then pass in 14.1mol of liquid ammonia, increase the temperature to 160℃, continue the reaction for 8h, and then lower the temperature to 40℃, drain the excess ammonia gas, open the kettle, add the obtained solid-liquid mixture to 800mL of water, continue to cool to 10℃, filter, add the resulting filter cake to the water, continue beating and filtering, the obtained solid is crystallized with methanol to obtain 388g , yield 91.2%, the purity of the liquid phase external standard is 99.5%. |
| Chemical Properties | yellow to orange powder |
| Uses | 5-Chloro-2-nitroaniline is a useful synthetic intermediate. It can be used as a reagent to synthesize benzamide derivatives as histone deacetylase inhibitors. It is an intermediate used to synthesize 1-Nitro Febantel a Febantel impurity. |
| Uses | 5-Chloro-2-nitroaniline was used in the synthesis of 5-(4-substituted piperazin-1-yl)-2-nitroanilines and 5-(4-substituted piperazin-1-yl)benzimidazole-2-carbamates. |
| Application | 5-Chloro-2-nitroaniline was used in the synthesis of 5-(4-substituted piperazin-1-yl)-2-nitroanilines and 5-(4-substituted piperazin-1-yl)benzimidazole-2-carbamates. The coupling of divinylbenzene cross-linked polystyrene with 5-chloro-2-nitroaniline followed by oxidative decyanation afforded benzophenone. |
2. Packaging
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping
4. Contact information
For more details, pls contact us freely.
Email address : elin@fdachem.com
Mob: 86 13613820652
WhatsApp/Skype/Wechat/LINE: 86 13613820652
Company Profile Introduction
Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.
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China
- Since: 2023-02-10
- Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro
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