Tetracycline
Price | $1 |
Package | 1KG |
Min. Order: | 1G |
Supply Ability: | 100KG |
Update Time: | 2019-07-06 |
Product Details
Product Name: Tetracycline | CAS No.: 60-54-8 |
Min. Order: 1G | Purity: 98% |
Supply Ability: 100KG | Release date: 2019/07/06 |
AD68
Tetracycline Basic information |
Product Name: | Tetracycline |
Synonyms: | 12,12a-pentahydroxy-6-methyl-1,11-dioxo-1;4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-Naphthacenecarboxamide;4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-4-(dimethylamino)-4;6-methyl-1,11-dioxy-2-naphthacenecarboxamide;abramycin;abricycline;achromycin(naphthacenederivative);achromycin(naphthracenederivatives) |
CAS: | 60-54-8 |
MF: | C22H24N2O8 |
MW: | 444.44 |
EINECS: | 200-481-9 |
Product Categories: | Antibiotic Explorer;Intermediates & Fine Chemicals;Pharmaceuticals;Antibacterial;Antibiotics;Antibiotics A to;Antibiotics by Application;Antibiotics T-ZAntibiotics;Chemical Structure Class;Genetic Marker SelectionAntibiotics;Interferes with Protein SynthesisSpectrum of Activity;L - ZAntibiotics;Mechanism of Action;Tetracyclines;Peptide Synthesis/Antibiotics;Inhibitors |
Mol File: | 60-54-8.mol |
Tetracycline Chemical Properties |
Melting point | 175-177 °C(lit.) |
alpha | D25 -257.9° (0.1N HCl); D25 -239° (methanol) |
Boiling point | 554.44°C (rough estimate) |
density | 1.3809 (rough estimate) |
refractive index | 1.6500 (estimate) |
storage temp. | 2-8°C |
solubility | 95% ethanol: soluble12.5mg/mL |
pka | pKa (50% aq DMF): 8.3, 10.2(at 25℃) |
color | yellow to yellow orange |
Water Solubility | Limited solubility in water. Soluble in 1M HCl with heating. |
Merck | 13,9271 |
CAS DataBase Reference | 60-54-8(CAS DataBase Reference) |
NIST Chemistry Reference | Tetracycline(60-54-8) |
EPA Substance Registry System | 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5, 5a,6,11,12a-octahydro-3,6, 10,12,12a-pentahydroxy-6- methyl-1,11-dioxo-, (4S,4aS,5aS,6S,12aS)-(60-54-8) |
Safety Information |
Hazard Codes | Xn,Xi |
Risk Statements | 22-36/37/38 |
Safety Statements | 22-36-26 |
WGK Germany | 3 |
RTECS | QI8750000 |
F | 3-8-10 |
HS Code | 29413000 |
Hazardous Substances Data | 60-54-8(Hazardous Substances Data) |
Toxicity | LD50 in rats, mice (mg/kg): 807, 808 orally (Goldenthal) |
Tetracycline Usage And Synthesis |
Chemical Properties | Crystalline Solid |
Uses | antibactierial |
Uses | antibacterial, antiamebic, antirickettsial |
Uses | Tetracycline is a linear, tetracyclic, broad spectrum antibiotic first prepared chemically by dechlorination of chlortetracycline and subsequently isolated from several Streptomyces species. Tetracycline has broad spectrum antibacterial and antiprotozoan activity, and acts by binding to the 30S and 50S ribosomal subunits blocking protein synthesis. Tetracycline is a pigment and, like many pigments, is degraded by light, oxygen, trace metal ions and pH variations. The purity of tetracycline is often variable, with significant levels of degradation products. |
Uses | Tetracycline is a broad spectrum polyketide antibiotic. It is used clinically to treat bacterial infections such as Rocky Mountain spotted fever, typhus fever, tick fevers, Q fever, and Brill-Zinsser disease. It is used to treat upper respiratory infections and acne. It is used to study multidrug resistance as well as potential side effects such as acute pancreatitis. |
Uses | Antibiotic substance produced by Streptomyces spp. Antiamebic; antibacterial; antirickettsial |
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates:
Pharmaceutical intermediates;
OLED intermediates;
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- Since: 2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
INQUIRY
楊俊青
sales@coreychem.com
sales@coreychem.com