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Postion:Product Catalog >Pharmaceutical intermediates>Heterocyclic compound>Pyridine compound>Methylpyridine>4-(Chloromethyl)pyridine hydrochloride
4-(Chloromethyl)pyridine hydrochloride
  • 4-(Chloromethyl)pyridine hydrochloride
  • 4-(Chloromethyl)pyridine hydrochloride
  • 4-(Chloromethyl)pyridine hydrochloride
  • 4-(Chloromethyl)pyridine hydrochloride
  • 4-(Chloromethyl)pyridine hydrochloride

4-(Chloromethyl)pyridine hydrochloride NEW

Price Get Latest Price
Package 25KG
Min. Order: 1KG
Supply Ability: 50000KG/month
Update Time: 2023-10-11

Product Details

Product Name: 4-(Chloromethyl)pyridine hydrochloride CAS No.: 1822-51-1
EC-No.: 217-350-7 Min. Order: 1KG
Purity: 99% Supply Ability: 50000KG/month
Release date: 2023/10/11

CAS:1822-51-1
MF:C6H6ClN.ClH
MW:164.03
EINECS:217-350-7
Product Categories:Pyridinium Compounds;blocks;Pyridines;Halides;Heterocycles;Pyridines, Pyrimidines, Purines and Pteredines;Pyridines derivates;Heterocyclic Compounds
Mol File:1822-51-1.mol
Article illustration

4-(Chloromethyl)pyridine hydrochloride Chemical Properties
Melting point 166-173 °C(lit.)
storage temp. Inert atmosphere,2-8°C
solubility soluble in DMSO, Methanol
form Fine Crystalline Powder
color Yellow to orange
Water Solubility 750 g/L (20 oC)
Sensitive Hygroscopic
BRN 3689154
CAS DataBase Reference1822-51-1(CAS DataBase Reference)
4-(Chloromethyl)pyridine hydrochloride Usage And Synthesis
Chemical PropertiesYELLOW TO ORANGE FINE CRYSTALLINE POWDER
UsesIt finds its application as a reagent for protection of carboxyl termini of peptides as 4-picolyl esters, providing a polar 'handle' which aids in separation and purification of the peptide. The group can be introduced in the presence of a base, e.g. tetramethylguanidine, is stable to acid-catalyzed removal of Cbz protecting group and can be removed by base, Na in liquid ammonia or catalytic hydrogenolysis. It is also applied in conjunction with Amberlyst?15 resin in peptide synthesis. It is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals.
Purification MethodsPurify it by recrystallisation from EtOH or EtOH/dry Et2O. It melts between 171o and 175o, and the clear melt resolidifies on further heating at 190o and turns red to black at 280o but does not melt again. The picrate-hydrochloride (prepared in EtOH) has m 146-147o. The free base is an oil. [Mosher & Tessieri J Am Chem Soc 73 4925 1951, Beilstein 20 III/IV 2752.]

Packing &shipping&Payment

Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
Quantity(Kilograms)1 - 10000>10000
Est. Time(days)5To be negotiated

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Article illustrationCompany information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.

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