3-Deazauridine NEW
Price | $48 | $77 | $118 |
Package | 25mg | 50mg | 100mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-01 |
Product Details
Product Name: 3-Deazauridine | CAS No.: 23205-42-7 |
Purity: 98.55% | Supply Ability: 10g |
Release date: 2024/11/01 |
Product Introduction
Bioactivity
名稱 | 3-Deazauridine |
描述 | 3-Deazauridine (NSC-126849) is a structural analog of uridine that inhibits the biosynthesis of Cytidine-5'-Triphosphate by competitive inhibition of Cytidine Triphosphate synthetase which is considered to be the primary mode of action of this nucleoside analog. |
體外活性 | 3-Deazauridine enhanced the in vitro antineoplastic action of 5-AZA-CdR on human leukemic cells by increasing its incorporation into DNA. Using an optimized dose-schedule we showed that this combination could cure some mice bearing L1210 leukemia, even in the presence of a subpopulation of drug-resistant (L1210/ARA-C) leukemic cells lacking DCK. 3-Deazauridine alone also cured some mice with L1210/ARA-C leukemia[1]. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 45 mg/mL (185.03 mM) DMF : 16 mg/mL |
關(guān)鍵字 | 3-Deazauridine | NSC126849 | NSC-126849 | 3Deazauridine | 3 Deazauridine |
相關(guān)產(chǎn)品 | Stavudine | 5-Fluorouracil | Capecitabine | Gemcitabine hydrochloride | 5-Azacytidine | Doxifluridine | 5-BrdU | Adenosine 5'-monophosphate disodium salt | Orotic acid | Ganciclovir |
相關(guān)庫 | DNA 損傷和修復(fù)分子庫 | 經(jīng)典已知活性庫 | 抑制劑庫 | 抗衰老化合物庫 | 已知活性化合物庫 | 抗癌化合物庫 | 核苷類化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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