3-Amino-1,2,4-triazole NEW
| Price | $41 |
| Package | 10g |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-27 |
Product Details
| Product Name: 3-Amino-1,2,4-triazole | CAS No.: 61-82-5 |
| Purity: 98.74% | Supply Ability: 10g |
| Release date: 2025/04/27 |
Product Introduction
Bioactivity
| Name | 3-Amino-1,2,4-triazole |
| Description | 3-Amino-1,2,4-triazole (Trapidil impurity B) is an inhibitor of catalase, capable of inducing the compensatory mechanism for hydrogen peroxide detoxification. This mechanism involves increasing the activities of glutathione peroxidase and glutathione reductase. |
| In vitro | 3-Amino-1,2,4-triazole (1,10 and 100 microg/ml ) had no significant cytotoxicity to the FRTL-5 cells (P > 0.05). The concentration of thyroglobulin (TG) in the culture was decreased by 10 and 100 microg/ml 3-Amino-1,2,4-triazole (P < 0.05), and the concentration of TG in the cells was decreased by 100 microg/ml (P < 0.05) but the TTF-1 in the cells were not obviously changed (P > 0.05). The TSHR in the surface of FRTL-5 cells was significantly decreased by all doses of 3-Amino-1,2,4-triazole (P < 0.01). The influence of 3-Amino-1,2,4-triazole on TG of FRTL-5 cells may be related to significantly reduce TSHR in the surface of FRTL-5 cells.[1] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 90.0 mg/mL (1070.4 mM), Sonication is recommended. |
| Keywords | ReactiveOxygenSpecies | Reactive Oxygen Species | Catalase | 3-Amino-1,2,4-triazole |
| Inhibitors Related | Cysteamine hydrochloride | Imeglimin hydrochloride | Acetylcysteine | L-Ascorbic acid | Hesperidin | Glucosamine | D-(+)-Glucono-1,5-lactone | 3-Indolepropionic acid | L-Ascorbic acid sodium salt | Sodium 2-oxopropanoate | Naringenin | Uric Acid |
| Related Compound Libraries | Pesticide Compound Library | NF-κB Signaling Compound Library | Bioactive Compound Library | Anti-Ovarian Cancer Compound Library | Anti-Obesity Compound Library | Inhibitor Library | Metabolism Compound Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Oxidation-Reduction Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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$30.00 / 5mg
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