2-Furoic acid NEW
| Price | $41 |
| Package | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-09 |
Product Details
| Product Name: 2-Furoic acid | CAS No.: 88-14-2 |
| Purity: 99.53% | Supply Ability: 10g |
| Release date: 2024/11/09 |
Product Introduction
Bioactivity
| 名稱 | 2-Furoic acid |
| 描述 | 2-Furoic acid (Furan-2-carboxylic acid) reduces serum cholesterol and triglyceride levels and exhibits anti-lipidemic effects. |
| 細(xì)胞實(shí)驗(yàn) | The inhibitory effects of 5-HMFA, FA, and a mixture of the furan-2-carboxylic acids on the swarming and swimming of P. collierea V5-G'5 were assayed on MW solid medium (pH 6.0) containing 0.3% washed agar. The concentrations of these compounds were determined by the concentrations found in 0.3% agar plates (1×), and a series of two fold dilutions ranging from 0.125× to 8× was tested. As 5-HMFA and FA remained in the washed agar at concentrations of 0.07 and 0.12 μg g?1 agar, respectively, the 0.3% agar medium supplemented with 0.125× furan-2-carboxylic acids, contained 0.32 ng mL?1 and 0.51 ng mL?1 FA, respectively[1]. |
| 動(dòng)物實(shí)驗(yàn) | When given orally twice daily for 4 weeks to 3-month-old ovariectomized (OVX) rats, Furan-2-carboxylic acid dose-dependently prevented bone loss, as monitored by bone densitometry, ash content, and urinary excretion of deoxypyridinoline.?No change in serum osteocalcin in the OVX rats by Furan-2-carboxylic acid suggested that bone formation might not be affected by the agent[2]. |
| 體外活性 | Agar that contains trace amounts of 5-HMFA and Furan-2-carboxylic acid inhibits the proliferation of some slow-growing or difficult-to-culture bacteria on the plates[1]. |
| 體內(nèi)活性 | 2-Furoic acid selectively inhibited bone resorbing activities of osteoclasts and prevented bone loss induced by estrogen deficiency but did not affect bone formation. 2-Furoic acid, an orally active selective human cathepsin K inhibitor, may have the therapeutic potential for the treatment of diseases characterized by excessive bone loss including osteoporosis[2]. |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 45 mg/mL (401.5 mM) |
| 關(guān)鍵字 | Diglyceride acyltransferase | Endogenous Metabolite | 2-Furoic acid | ATP Citrate Lyase | inhibit | Diacylglycerol acyltransferase | ACLY | mono- acylglycerol acyltransferase | Inhibitor | 2Furoic acid | Acyltransferase | acyl-CoA:cholesterol acyltransferase | 2 Furoic acid |
| 相關(guān)產(chǎn)品 | Sucrose | Ferulic Acid | Glycerol | Thymidine |
| 相關(guān)庫(kù) | 經(jīng)典已知活性庫(kù) | 風(fēng)味化合物庫(kù) | 天然產(chǎn)物庫(kù) | 煙草單體化合物庫(kù) | 已知活性化合物庫(kù) | 腸道微生物代謝化合物庫(kù) | 藥食同源庫(kù) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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