2-Bromohexadecanoic acid NEW
| Price | $37 | $59 | $90 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: 2-Bromohexadecanoic acid | CAS No.: 18263-25-7 |
| Purity: 97% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | 2-Bromohexadecanoic acid |
| Description | 2-Bromohexadecanoic acid (2-BP) is a non-metabolizable palmitate analog, an agonist of PPARδ, which acts as a palmitoylation inhibitor and inhibits DHHC-mediated palmitoylation. |
| In vitro | METHODS: HepG2 was treated with PA (200 μM) and 2-Bromohexadecanoic acid (25-150 μM) to examine CSC sphere morphology and number. RESULTS: 2-Bromohexadecanoic acid (25, 50 and 150 μM) significantly reduced PA-induced CSC sphere formation in HepG2 (75-150 μM and >150 μM.[1]) METHODS: ERα or ERα-Cys447Ala-transfected HeLa and HepG2 cells were pretreated with 2-Bromohexadecanoic acid (10 μM) for 30 min, then stimulated with E2 (10 nM) for 10 min, and the target protein expression levels were detected by Western Blot. RESULTS: E2 induced ERK and AKT phosphorylation in ERα-transfected HeLa and HepG2 cells. E2-induced signaling kinase activation was completely blocked without affecting the basal level of phosphorylation if the cells were pretreated with the PAT inhibitor 2-Bromohexadecanoic acid.E2 was ineffective in inducing phosphorylation of ERK and AKT in ERα-Cys447Ala mutant-transfected HeLa cells. [2] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | Methanol : 100 mg/mL DMSO : 60 mg/mL (178.93 mM) |
| Keywords | 2Bromohexadecanoic acid | 2 Bromohexadecanoic acid |
| Related Compound Libraries | Nuclear Receptor Compound Library | Bioactive Compound Library | Inhibitor Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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