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1G244 NEW

Price	$33	$53	$106
Package	5mg	10mg	25mg

Min. Order:
Supply Ability:	10g
Update Time:	2024-11-19

Product Details

Product Name: 1G244	CAS No.: 847928-32-9
Purity: 98.23%	Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

Name	1G244
Description	1G244 is an inhibitor of DPP8/9 with antiatherosclerotic and antimyeloma properties. 1G244 had the IC50 values of 14 and 53 nM against DPP8 and DPP9, and The Ki values for 1G244 were 0.9 and 4.2 nM for DPP8 and DPP9
In vitro	1G244 (0-100 μM) dose-dependently decreased viable cell number of five multiple myeloma cell lines as well as three T-cell lymphoma cell lines[2].
In vivo	The apoE?/? mice treated with 1G244 (1G244 dissolved in 75% PEG 300, 2 mg/kg) showed that 1G244 reduced the area of advanced atherosclerotic lesions by about 14%[1]. 1G244 was administered subcutaneously into mice at 30?mg/kg once a week, administration of 1G244 apparently suppressed the subcutaneous growth of MM.1?S cells[2].
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	DMSO : 225.0 mg/mL (445.9 mM), Sonication is recommended.
Keywords	1G-244 \| 1G 244 \| 1G244
Inhibitors Related	Sitagliptin \| Teneligliptin hydrobromide \| Sitagliptin phosphate monohydrate \| Anagliptin \| TCH-165 \| Racecadotril \| Linagliptin \| Aprotinin \| Vildagliptin \| Alloxan monohydrate \| 4'-Hydroxychalcone \| Bortezomib
Related Compound Libraries	Bioactive Compound Library \| Inhibitor Library \| Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.