WHAT IS CB-03-01?

CB-03-01 is a molecule that acts at the level of the skin androgen receptor, blocking dihydrotestosterone (DHT) from binding to
the receptor in the cell. The molecule has a unique mechanism that acts at the skin surface, and is quickly metabolized to free
inactive cortexolone, a substance naturally found in the body. The molecule has been evaluated in a variety of animal models as
well as initial human trials in Europe for acne and androgenic alopecia. The results of these studies demonstrate that CB-03-01
appears to have potent anti-androgenic activity without significant local or systemic side effects.

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