Nitrogen mustard is the first anti-tumor drug that has been used clinically and has achieved outstanding efficacy, and is a representative of dichloroethylamine alkylating agents. For many years, the topical application of chlorambucil hydrochloride has achieved a more significant effect in the treatment of vitiligo, but its adverse reactions should also be paid attention to, mainly the local irritation of the skin and mucous membranes, and occasionally allergic reactions may also cause squamous cell carcinoma and cherry. Reports of hemangioma