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Postion:Product Catalog >API>Nervous system drugs>Tianeptine
Tianeptine
  • Tianeptine
  • Tianeptine
  • Tianeptine
  • Tianeptine
  • Tianeptine

Tianeptine

Price $1
Package 1g
Min. Order: 5g
Supply Ability: 1000kgs/month
Update Time: 2024-02-22

Product Details

Product Name: Tianeptine CAS No.: 66981-73-5
EC-No.: 614-004-0 Min. Order: 5g
Purity: 99%min Supply Ability: 1000kgs/month
Release date: 2024/02/22

Detail:

CAS:66981-73-5
MF:C21H25ClN2O4S
MW:436.95
EINECS:250-059-3
Melting point:129-131°C
RIDADR 3249
HazardClass 6.1(b)
PackingGroup III
Minimum Order Quantity: 100G
Delivery Time: About 4-7 working days
Payment Terms: T/T, Western Union, MoneyGram,Bitcoin

 

Superiority:

Yuanhang Bio-pharmaceutical Technology Co.,Ltd achieves millions of US dollars of salesrevenue in recent years. And there are currently over 400 employers, researchers accounting for 37%. We conducted more than 50 kinds of scientific research, and enjoy more than 20 national patents. We have even acquired national invention patent certificate. 5, 184 products of us are almost unique around the world. Our company's various raw chemical materials are of reliable quality, most of which conform to the requirements of FCC, USP and BP, it is mainly sold to pharmacy companies and health care companies abroad. Our target markets comprise of USA, Canada, UK, Brazil, Netherlands, Ireland, New Zealand, Austria, Australia and so on.

 

Description:

Tianeptine is neuroprotective via multiple neurochemical and cellular mechanisms. In theory, tianeptine's neuroprotective action makes it a potential life-extension drug. When an organism is under stress, or perceives itself under stress, the hypothalamus secretes corticotropin-releasing hormone/factor (CRH/CRF). CRH/CRF in turn increases secretion of adrenocorticotrophic hormone (ACTH) from the anterior pituitary. ACTH in turn stimulates the release of glucocorticoids from the adrenal cortex. Persistent, uncontrolled physical and psychosocial stress causes excess cortisol secretion from the adrenal glands. Excess cortisol causes dendritic shrinkage in the hippocampus and a contrasting growth of dendrites in the lateral amygdala. These stress-induced changes tend to lower mood; they can cause clinical depression in the genetically vulnerable. Current evidence suggests that tianeptine acts to prevent and even reverse stress-induced neural damage, promoting both neuronal survival and synaptic plasticity.

 

COA:

 

TestsSpecificationsResults
DescriptionWhite to yellowish powder, very hygroscopic.Off-white powder, very hygroscopic.
SolubilityFreetly soluble In water and methanol and dichloromethaneComplies
Identification(1)By IR, To match with working standardComplies
(2)It gives reaction of sodiumComplies
Impurities A≤0.1%Not detected
Related compoundsAny impurity ≤0.1%<0.1%
Total impurities ≤0.4%0.25%
Residual SolventsAcetidin≤ 0.5%Not detected
Dichloromethane≤ 0.06%Not detected
Methanol≤ 0.3%Not detected
Acetone ≤ 0.5%Not detected
Acetonitrile≤0.041%Not detected
Ethanol≤0.5%0.04%
N, N-dimethylformamide≤0.088%Not detected
Water≤ 5.0%1.38%
Assay99.0%-101.0%(On anhydrous basis)99.98%
ConclusionConform to EP8.0

 

Applicant:

Tianeptine has strong antidepressant and anxiolytic properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in elderly patients and in those following alcohol withdrawal; such patients can be more sensitive to the adverse effects of psychotropic drugs. Recent interesting results indicate anticonvulsant and analgesic activity of tianeptine and its possible interaction with adenosine A1 receptors.


Company Profile Introduction

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