Product Details
| Product Name:
Alizapride |
CAS No.:
59338-93-1 |
| Min. Order:
1KG |
Purity:
95%~99.99% |
| Supply Ability:
10 MT/ Month |
Release date:
2024/10/22 |
Heidi 108
| Alizapride Basic information |
| Product Name: |
Alizapride |
| Synonyms: |
ALIZAPRIDE;n-(1-allyl-2-pyrrolidinylmethyl)-6-methoxy-1h-benzotriazole-5-carboxamide;1h-benzotriazole-5-carboxamide,6-methoxy-n-((1-(2-propenyl)-2-pyrrolidinyl)met;6-methoxy-n-((1-(2-propenyl)-2-pyrrolidinyl)methyl)-1h-benzotriazole-5-carbo;Nausilen;Plitican;Vergentan;6-Methoxy-N-{[1-(2-propnyl)-2-pyrrolidinyl]methyl]-1H-benzotriazole-5-carboxamide |
| CAS: |
59338-93-1 |
| MF: |
C16H21N5O2 |
| MW: |
315.37 |
| EINECS: |
261-710-6 |
| Product Categories: |
|
| Mol File: |
59338-93-1.mol |
 |
| |
| Alizapride Chemical Properties |
| Melting point |
139° |
| Boiling point |
580.3±40.0 °C(Predicted) |
| density |
1.224±0.06 g/cm3(Predicted) |
| pka |
7.09±0.40(Predicted) |
| CAS DataBase Reference |
59338-93-1(CAS DataBase Reference) |
| Toxicity |
LD50 i.v. in mice (5 days): 92.7 mg/kg (Bulteau) |
| |
| Alizapride Usage And Synthesis |
| Originator |
Plitican ,Delagrange ,France ,1981 |
| Manufacturing Process |
38.6 g (0.2 mol) of 2-methoxy-4,5-azimidobenzoic acid were dissolved in anhydrous toluene and 56 g (0.4 mol) of 1-allyl-2-amino-methylpyrrolidine were added. The mixture was heated to 50°C and then 42 g (0.3 mol) of phosphoric anhydride were added. The mixture was warmed at reflux temperature for 3 hours and then cooled to 80°C. After adding water, the aqueous layer was alkalized. The crystals were filtered, washed with water and then dissolved in 450 ml of acetone. After crystallization, the product was 40.4 g (yield 65%) of N-(1'-allyl-2'-pyrrolidylmethyl)-2-methoxy-4,5- azimidobenzamide having a melting point of 139°C were obtained. |
| Therapeutic Function |
Neuroleptic, Antiemetic |
Company Profile Introduction
Technology research and transfer of pilot screening, pilot scale-up and mass production solutions , for pharmaceutical intermediates, biologicals and fine chemicals (Not including inflammable , explosive , hazardous goods ) ; Market : Nano material , metal catalyst , raw material of cosmetics , pharmaceutical intermediates , chemicals , photoelectric material , import and export of technology and goods (For projects subject to approval according to law, business activities can be carried out only after approval by relevant departments ).
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