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Postion:Product Catalog >Analytical Chemistry>Standard>Pharmaceutical Impurity Reference Standards>Paricalcitol
Paricalcitol
  • Paricalcitol

Paricalcitol

Price
Package
Min. Order: 25Kg/Bag
Supply Ability: 20 Tons
Update Time: 2020-11-16

Product Details

Product Name: Paricalcitol CAS No.: 131918-61-1
EC-No.: 658-064-6 Min. Order: 25Kg/Bag
Purity: 99% Supply Ability: 20 Tons
Release date: 2020/11/16
Product Name:
Paricalcitol
Synonyms:
PARICALCITOL (10 MG)F0E3030.997MG/MG(AI);PARICALCITOL;19-nor-1alpha,25-dihydroxyvitamin D2;(1R,3R)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5S)-6-Hydroxy-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]cyclohexane-1,3-diol;Zemplar;1,3-Cyclohexanediol, 5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E,4S)-5-hydroxy-1,4,5-trimethyl-2-hexen-1-yl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3R,5Z)-;Paricalcitol (10 mg) (COLD SHIPMENT REQUIRED);(1R,3R,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-Octahydro-1-[(1R,2E,4S)-5-hydroxy-1,4,5-triMethyl-2-hexen-1-yl]-7a-Methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol
CAS:
131918-61-1
MF:
C27H44O3
MW:
416.64
EINECS:
658-064-6
Product Categories:
-;Vitamin D3 analogs;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:
131918-61-1.mol
Article illustration
 
Paricalcitol Chemical Properties
Boiling point 
564.8±50.0 °C(Predicted)
density 
1.121±0.06 g/cm3(Predicted)
Fp 
14℃
pka
14.34±0.40(Predicted)
form 
neat
InChIKey
BPKAHTKRCLCHEA-UBFJEZKGSA-N
CAS DataBase Reference
131918-61-1(CAS DataBase Reference)
 
Safety Information
RIDADR 
UN1170 - class 3 - PG 2 - Ethanol, solution
HS Code 
2936299055
Hazardous Substances Data
131918-61-1(Hazardous Substances Data)
 
MSDS Information
 
 
Paricalcitol Usage And Synthesis
Description
Paricalcitol was launched as Zemplar in the US for the prevention and treatment of secondary hyperthyroidism associated with chronic renal failure. Paricalcitol is a synthetic vitamin D2, namely a novel 1-alpha-hydroxy-19-noranalogue in which the ring A exocyclic methylene group, typical of all vitamin D systems, has been replaced by two hydrogen atoms. Paricalcitol is the first vitamin D analogue marketed for this indication. In patients with chronic renal failure, Paricalcitol appreciably reduced levels of parathyroid hormone (PTH) without a significant difference in the incidence rate for hypercalcemia or hyperphosphatemia when compared with placebo.
Chemical Properties
White Solid
Originator
Abbott (US)
Uses
Synthetic analog of vitamin D. Antihyperparathyroid.
Uses
Antihyperparathyriod
Uses
1,25-Dihydroxy vitamin D2 is a potent agonist of the vitamin D receptor. Paricalcitol is a synthetic 1,25-dihydroxy vitamin D2 analog. As vitamin D deficiency, associated with chronic kidney disease, leads to an increase in parathyroid hormone (secondary hyperparathyroidism), paricalcitol is used in renal patients to block parathyroid hormone overproduction. Vitamin D deficiency is also a risk factor in cancer, cardiovascular disease, hypertension, and diabetes, and paricalcitol may have applications in those contexts as well.
Brand name
Zemplar (Abbott).

Company Profile Introduction

Longyan Tianhua Biological Technology Co., Ltd is located in Longyan city, Fujian Province, China. It is a large-scale high-tech integrated enterprise dedicated to the research, development and sales of fine chemicals, pharmaceutical raw material intermediates, food and feed additives. The company has its own research and development base, equipped with advanced production equipment and efficient and precise testing instruments, has set up a strict and scientific quality management system, and constantly committed to technological innovation, product innovation and management innovation, so as to ensure that our products have super competitiveness in the same industry.? Company's main: Phenformin Hydrochloride, Chlorhexidine Acetate, Indomethacin Biphenyl benzyl azole dyclonine hydrochloride clorprenaline hydrochloride griseofulvin chloramphenicol maleic acid to guangxi pp qi, fucus xanthine tert-butyl of hydroxy anisole (BHA), ammonia, benzene pteridine zonisamide moxifloxacin mother nucleus moxifloxacin side chain moxifloxacin hydrochloride clobetasol propionate tranexamic acid raw material, and so on.? The annual sales volume of the company is around 3 million DOLLARS. Its products have been sold to more than 40 countries and regions all over the world, and have been well received. Moreover, the buyback rate of customers is very high. Longyan Tianhua Biotechnology Co., LTD. Is looking forward to long-term cooperation with you.

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  • Since: 2019-10-11
  • Address: Room 201, 11 Xinhouying Road, Xicheng Lian, Xinluo District, Longyan City, Fujian Province, China
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