![2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3](https://img.chemicalbook.com/ProductImageEN/2020-11/Large/d1d4f836-a431-4381-b53b-c17762819378.jpg)
2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3
Price |
Package |
Min. Order: | 25Kg/Bag |
Supply Ability: | 20 Tons |
Update Time: | 2020-11-16 |
Product Details
Product Name: 2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3 | CAS No.: 104121-92-8 |
EC-No.: 686-849-3 | Min. Order: 25Kg/Bag |
Purity: 99% | Supply Ability: 20 Tons |
Release date: 2020/11/16 |
2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3 Basic information |
Product Name: | 2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3 |
Synonyms: | 2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3;Eldecalcitol;ED-71;Eldecalcitol(ED-71);2.beta.-(3-Hydroxypropoxy)-1.alpha.,25-dihydroxyvitaMin D3;(1R,Z)-5-((E)-2-((1R,7aR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-2-(3-hydroxypropoxy)-4-methylenecyclohexane-1,3-diol;1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)vitamin D3 |
CAS: | 104121-92-8 |
MF: | C30H50O5 |
Mol File: | 104121-92-8.mol |
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2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3 Chemical Properties |
Melting point | 126-128℃ |
density | 1.10 |
Safety Information |
MSDS Information |
2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3 Usage And Synthesis |
Description | Eldecalcitol (Edirol) was approved in January 2011 by the Japanese Ministry of Health, Labor, and Welfare for the treatment of osteoporosis. Because of vitamin D’s central role in the bone health, vitamin D and analogs of vitamin D have been used to treat patients diagnosed with osteoporosis. Eldecalcitol is an analog of the active form of vitamin D, calcitriol, in which the lower cyclohexane ring contains a hydroxypropyl group. The synthesis of eldecalcitol involves the assembly of two units, a fully protected (3S,4S,5R)-oct-1-en-7-yne-3,4,5-triol and a fused bicyclic system, (R)-6- ((1R,3aR,7aR,E)-4-(bromomethylene)-7a-methyloctahydro-1H-inden-1- yl)-2-methylheptan-2-ol, through a Diels-Alder reaction to give fully protected eldecalcitol. The hydroxyl groups are then deprotected to give the parent molecule. Eldecalcitol binds to the vitaminDreceptor 2.7-fold more potently than calcitriol, while only weakly inhibiting serum parathyroid hormone. |
Originator | Chugai Pharmaceutical/Roche (Japan) |
Definition | ChEBI: A hydroxycalciol that is calcitriol with a 3-hydroxypropoxy group at position 2 |
Company Profile Introduction
Longyan Tianhua Biological Technology Co., Ltd is located in Longyan city, Fujian Province, China. It is a large-scale high-tech integrated enterprise dedicated to the research, development and sales of fine chemicals, pharmaceutical raw material intermediates, food and feed additives.
The company has its own research and development base, equipped with advanced production equipment and efficient and precise testing instruments, has set up a strict and scientific quality management system, and constantly committed to technological innovation, product innovation and management innovation, so as to ensure that our products have super competitiveness in the same industry.?
Company's main: Phenformin Hydrochloride, Chlorhexidine Acetate, Indomethacin Biphenyl benzyl azole dyclonine hydrochloride clorprenaline hydrochloride griseofulvin chloramphenicol maleic acid to guangxi pp qi, fucus xanthine tert-butyl of hydroxy anisole (BHA), ammonia, benzene pteridine zonisamide moxifloxacin mother nucleus moxifloxacin side chain moxifloxacin hydrochloride clobetasol propionate tranexamic acid raw material, and so on.?
The annual sales volume of the company is around 3 million DOLLARS. Its products have been sold to more than 40 countries and regions all over the world, and have been well received. Moreover, the buyback rate of customers is very high.
Longyan Tianhua Biotechnology Co., LTD. Is looking forward to long-term cooperation with you.
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- Since: 2019-10-11
- Address: Room 201, 11 Xinhouying Road, Xicheng Lian, Xinluo District, Longyan City, Fujian Province, China
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