α-Solanine NEW
| Price | $68 | $172 | $272 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-06 |
Product Details
| Product Name: α-Solanine | CAS No.: 20562-02-1 |
| Purity: 99.37% | Supply Ability: 10g |
| Release date: 2024/11/06 |
Product Introduction
Bioactivity
| 名稱 | α-Solanine |
| 描述 | α-Solanine (alpha-Solanine) is an alkaloid derived from potato with anticancer and antitumor activity, attenuating chondrocyte death by inhibiting the NF-κB pathway. α-Solanine inhibits the proliferation and migration of glioma cells but promotes apoptosis of glioma cells. |
| 體外活性 | METHODS: α-solanine (3, 6, 9, 12 μg/μl) was used to treat PANC-1, sw1990 and MIA PaCa-2 cells for 24 h or 48 h, and the viability of cells was observed. RESULTS: After treatment with α-solanine (12 μg/μl), the cell viability was significantly decreased. At α-solanine concentrations of 3, 6, and 9 μg/μl, and treatment time of 24 h and 48 h, α-solanine did not cause cytotoxicity in the cells of each cell line. α-Solanine (3, 6 and 9 μg/μl) significantly reduced the mRNA and protein expression of VEGF in PANC-1 cells in a dose-dependent manner, while α-solanine inhibited angiogenesis by inhibiting VEGF expression.[1] |
| 體內(nèi)活性 | METHODS: 1 μl/g of α-solanine was injected into the peritoneal cavity of each mouse for two weeks. The body weight of the mice and the size of their tumors were measured daily. RESULTS: α-solanine inhibited the growth of PANC-1 tumor xenografts, reducing tumor volume by 61% (P<0.05). [1] |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 30 mg/mL (34.56 mM), Sonication is recommended. |
| 關(guān)鍵字 | α-Solanine | a-Solanine | αSolanine | α Solanine |
| 相關(guān)產(chǎn)品 | Stavudine | 5-Fluorouracil | Myricetin | Sodium 4-phenylbutyrate | L-Ascorbic acid | Dextran sulfate sodium salt (MW 4500-5500) | Metronidazole | Sorafenib | Tributyrin | Diallyl disulfide |
| 相關(guān)庫 | 抗癌天然產(chǎn)物庫 | 中藥單體化合物庫 | 經(jīng)典已知活性庫 | 高通量篩選天然產(chǎn)物庫 | 抗衰老化合物庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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