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Postion:Product Catalog >δ-secretase inhibitor 11
δ-secretase inhibitor 11
  • δ-secretase inhibitor 11

δ-secretase inhibitor 11 NEW

Price $30 $43 $97
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: δ-secretase inhibitor 11 CAS No.: 842964-18-5
Purity: 99.4% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

Nameδ-secretase inhibitor 11
Descriptionδ-secretase inhibitor 11 is an inhibitor of δ-secretase and can be used as a lead compound for translational development of AD treatment.
In vitroThe inhibitory effect of δ-secretase inhibitor 11 on AEP activity in vitro was tested and the dose-response relationship revealed that the δ-secretase inhibitor 11 had an IC50 value of 0.15?±?0.09?μM [1].
In vivoIt was found that oral administration of δ-secretase inhibitor 11 (10?mg/kg) significantly suppressed brain AEP activity compared to the vehicle treatment. The concentrations of Aβ1–40 and Aβ1–42 in brain lysates of SAMP8 mice were significantly reduced due to AEP inhibition by δ-secretase inhibitor 11. [1]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 2.2 mg/mL (10 mM)
Keywordsδ-Secretase inhibitor 11 | CNS diseases | Alzheimer's disease | δ secretase inhibitor 11 | Caspase | β-amyloid peptide | δ-secretase inhibitor 11 | oxygen-glucose deprivation | amyloid precursor protein | Abeta | asparagine endopeptidase | Inhibitor | APP | AEP | Amyloid-β | delta-secretase inhibitor 11 | Pala cells | δsecretase inhibitor 11 | inhibit
Inhibitors RelatedAnle138b | Notoginsenoside R1 | Geniposide | Deferoxamine Mesylate | Tramiprosate | SKLB-163 | Dihydroergocristine mesylate | Rutin | Taurochenodeoxycholic Acid | Tauroursodeoxycholate sodium | Tauroursodeoxycholate | Methyl tridecanoate
Related Compound LibrariesBioactive Compound Library | Neuronal Signaling Compound Library | Pyroptosis Compound Library | Inhibitor Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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