S-ALLYL-L-CYSTEINE NEW

Price	$8	$6	$1
Package	1KG	25KG	100KG

Min. Order:	1KG
Supply Ability:	g-kg-tons, free sample is available
Update Time:	2024-03-29

Product Details

Product Name: S-ALLYL-L-CYSTEINE	CAS No.: 21593-77-1
Min. Order: 1KG	Purity: 99%
Supply Ability: g-kg-tons, free sample is available	Release date: 2024/03/29
Lead time: In stock, ready for shipment	Packaging: bag/bottle/drum/IBC
Delivery: By express, by air, by sea	Origin: Manufacturer, advantage product
CCOA, MSD: Available, contact us for details	Name: Sun

1. Materials information

Name	s-allyl-l-cysteine
Synonym	More Synonyms

Description	S-Allyl-L-cysteine, one of the organosulfur compounds found in AGE, possess various biological effects including neurotrophic activity, anti-cancer activity, anti-inflammatory activity.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Cancer Research Areas >> Neurological Disease Natural Products >> Others Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease Research Areas >> Others
In Vitro	It is found that S-Allyl-L-cysteine could protect against amyloid-protein (A)-and tunicamycin-induced cell death in differentiated PC12 cells. Simultaneously applied S-Allyl-L-cysteine (1 μM) suppresses the cell death induced by Aβ25-35 and Aβ1-40 in a concentration-dependent manner, and neuronal integrity is almost completely retained. Simultaneously applied S-Allyl-L-cysteine significantly decreases the Aβ-induced level of ROS. The TEAC value of S-Allyl-L-cysteine is lower than that of oxidized GSH, and no antioxidant activity is observed. Intracellular GSH levels remains unaffected by treatment of neurons with S-Allyl-L-cysteine for 24 h. Furthermore, the increase in caspase-12 protein expression is suppressed by simultaneously adding 1 μM S-Allyl-L-cysteine [1]. S-Allyl-L-cysteine up to a concentration 1.0 mM does not exhibit any cytotoxic impact on morphology of myoblast and myotubes in culture observed under bright field microscope. TNF treatment leads to a significant decrease in the intracellular CK activity while S-Allyl-L-cysteine pre-treatment to TNF treated myotubes decreases the release of CK in media. S-Allyl-L-cysteine pre-treatment decreases the level of active form of this enzyme in S-Allyl-L-cysteine+TNF group. Similar observations are recorded at mRNA level for caspase-3. These results illustrate that S-Allyl-L-cysteine regulates apoptotic signals via suppressing the transcription and thus protein expression of caspase-3[2].
References	[1]. Kosuge Y, et al. S-allyl-L-cysteine selectively protects cultured rat hippocampal neurons from amyloid beta-protein- and tunicamycin-induced neuronal death. Neuroscience. 2003;122(4):885-95. [2]. Dutt V, et al. S-allyl cysteine inhibits TNFα-induced skeletal muscle wasting through suppressing proteolysis and expression of inflammatory molecules. Biochim Biophys Acta. 2018 Apr;1862(4):895-906.

Density	1.191
Boiling Point	300 oC
Melting Point	235-236 oC
Molecular Formula	C₆H₁₁NO₂S
Molecular Weight	161.222
Flash Point	135 oC
Exact Mass	161.051056
PSA	88.62000
LogP	1.31
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.543
Storage condition	2-8°C

S-Allyl-L-cysteine MSDS(Chinese)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H317
Precautionary Statements	P280
Hazard Codes	F,C
Risk Phrases	R11:Highly Flammable. R22:Harmful if swallowed. R34:Causes burns. R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
Safety Phrases	S16-S26-S36/37/39-S45
RIDADR	UN 2379 3/PG 2
WGK Germany	3
RTECS	EO4460000
Packaging Group	II
Hazard Class	3.1
HS Code	2930909090

N-Boc-S-allyl-L...

232953-12-7

~56%

S-Allyl-L-cyste...

21593-77-1

Literature: ISIS INNOVATION LIMITED Patent: US2012/178913 A1, 2012 ; Location in patent: Page/Page column 10-11 ;

L-Cysteine hydr...

52-89-1

allyl bromide

106-95-6

~70%

S-Allyl-L-cyste...

21593-77-1

Literature: Maldonado, Perla D.; Alvarez-Idaboy, J. Raul; Aguilar-Gonzalez, Adriana; Lira-Rocha, Alfonso; Jung-Cook, Helgi; Medina-Campos, Omar Noel; Pedraza-Chaverri, Jose; Galano, Annia Journal of Physical Chemistry B, 2011 , vol. 115, # 45 p. 13408 - 13417

L-cysteine

52-90-4

allyl bromide

106-95-6

~84%

S-Allyl-L-cyste...

21593-77-1

Literature: Koch; Keusgen, Michael Pharmazie, 1998 , vol. 53, # 10 p. 668 - 671

Precursor 10	Previous 1/3 Next
CAS#:232953-12-7 N-Boc-S-allyl-L... CAS#:52-89-1 L-Cysteine hydr... CAS#:106-95-6 allyl bromide CAS#:52-90-4 L-cysteine
DownStream 9	Previous 1/3 Next
CAS#:2179-57-9 Diallyl disulfide CAS#:539-86-6 Allicin CAS#:127-17-3 Pyruvic acid CAS#:52-90-4 L-cysteine

HS Code	2930909090
Summary	2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

2. Packaging of materials

For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.

Or smaller package 1kg/bottle, 10kgs/bottle as request.

Article illustration

3. Shipping & Delivery

By Express

Provide door to door service

Suitable for goods under 50kg

Delivery: 3-7 days

Cost: low cost

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By Air

Provide airport to airport service

Suitable for goods over 50kg

Delivery: 3-14 days

Cost: high cost

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By Sea

Provide seaport to seaport service

Suitable for goods over 100kg

Delivery: 2-45 days

Cost: low cost

Article illustration

4. Contact information

For more details, pls contact us freely.

Email address: Sun@fdachem.com

Mob: 86 13526505137

WhatsApp/Skype/Wechat/LINE: 86 13526505137

Company Profile Introduction

Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.

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