(-)-Oxypeucedanin hydrate NEW
| Price | $98 | $247 | $372 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-14 |
Product Details
| Product Name: (-)-Oxypeucedanin hydrate | CAS No.: 133164-11-1 |
| Purity: ≥95% | Supply Ability: 10g |
| Release date: 2024/11/14 |
Product Introduction
Bioactivity
| 名稱 | (-)-Oxypeucedanin hydrate |
| 描述 | (-)-Oxypeucedanin hydrate is a furanocoumarin. It has a role as a metabolite. |
| 細(xì)胞實(shí)驗(yàn) | Pure compounds were isolated from the extract of aerial parts of the plant by chromatographic methods.Bioactivities were tested on multidrug resistant and sensitive mouse T-lymphoma cell lines.The inhibition of the cancer MDR efflux pump ABCB1 was evaluated by flow cytometry (at 2 and 20 μM).A checkerboard microplate method was applied to study the interactions of furocoumarins and doxorubicin.Toxicity was studied using normal murine NIH/3T3 fibroblasts. |
| 體外活性 | Oxypeucedanin exhibited marginal toxicity on normal fibroblast cells and sensitive parental mouse lymphoma cells;?furthermore, they were less toxic on multidrug resistant lymphoma cells.? Oxypeucedanin showed moderate MDR reversing activity.?In the checkerboard assay, oxypeucedanin and heraclenin showed slight synergistic effect with doxorubicin.?These compounds might improve the cytotoxic effect of the standard chemotherapeutic drug doxorubicin. |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 55 mg/mL (180.75 mM) |
| 關(guān)鍵字 | cytotoxic | ( ) Oxypeucedanin hydrate | cell | tumor | inhibit | Inhibitor | ()Oxypeucedanin hydrate | antiproliferative | cancer | Oxypeucedanin Hydrate |
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Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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