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Postion:Product Catalog >Biochemical Engineering>Inhibitors>Immunosuppressants> NAFAMOSTAT MESYLATE
	NAFAMOSTAT MESYLATE
  • 	NAFAMOSTAT MESYLATE
  • 	NAFAMOSTAT MESYLATE

NAFAMOSTAT MESYLATE NEW

Price $8 $5 $1
Package 1kg 25kg 100kg
Min. Order: 1kg
Supply Ability: g-kg-tons, free sample is available
Update Time: 2024-04-05

Product Details

Product Name: NAFAMOSTAT MESYLATE CAS No.: 81525-10-2
Min. Order: 1kg Purity: 99%
Supply Ability: g-kg-tons, free sample is available Release date: 2024/04/05
Lead time: In stock Packaging: bottle/drum/bucket/IBC, as request.
Delivery: By sea, by air, by express Origin: Manufacturer
NAME: Sun

1. Product information

 Names

Namenafamostat mesylate
SynonymMore Synonyms

 Nafamostat Biological Activity

DescriptionNafamostat is a broad spectrum serine protease inhibitor, kallikrein inhibitor, and inhibits blood coagulation; is also a possible complement inhibitor.Target: Serine ProteaseTranilast (FUT-175) is an antiallergic drug for bronchial asthma. It has been used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis. It has also been investigated for use as an antiproliferative drug on drug-eluting stents.A 20-40 mg/h dose of FUT-175 prolonged coagulation time sufficiently in the instrumental blood of the extracorporeal circuit but not in the systemic blood. Its anticoagulant activity decreased immediately after hemodialysis. Therefore, we could manage all patients without any bleeding trouble during hemodialysis with FUT-175 as an anticoagulant. Although there were side effects of FUT-175, such as nausea, vomiting, itching and eruption, they were not serious, and FUT-175 could be administered without interruption. FUT-175 seems to be useful as an anticoagulant during hemodialysis for patients susceptible to bleeding.
Related Catalog
Signaling Pathways >> Metabolic Enzyme/Protease >> Ser/Thr Protease
Research Areas >> Cardiovascular Disease
References

[1]. Ikehara S, et al. Effect of FUT-175, a new synthetic protease inhibitor, on the development of lupus nephritis in (NZB x NZW) F1 mice. Immunology. 1985 Aug;55(4):595-600.

[2]. Pak K, et al. Effectiveness of FUT-175, protease inhibitor, as an anticoagulant to hemodialysis. Hinyokika Kiyo. 1988 Jun;34(6):1077-81.

 Chemical & Physical Properties

Density1.4±0.1 g/cm3
Boiling Point637.2±65.0 °C at 760 mmHg
Molecular FormulaC19H17N5O2
Molecular Weight347.371
Flash Point339.1±34.3 °C
Exact Mass347.138214
PSA138.07000
LogP1.93
Vapour Pressure0.0±1.9 mmHg at 25°C
Index of Refraction1.694
Storage condition2-8℃

 Synonyms

6-Carbamimidoyl-2-naphthyl 4-carbamimidamidobenzoate
6-carbamimidoylnaphthalen-2-yl 4-carbamimidamidobenzoate
Nafamostat Dimethanesulfonate
NAFAMOSTAT MESILATE
Benzoic acid, 4-[(aminoiminomethyl)amino]-, 6-(aminoiminomethyl)-2-naphthalenyl ester
6-Amidino-2-naphthyl-4-guanidinobenzoate
Futhan
6-AMIDINO-2-NAPHTHYL-4-GUANIDINOENZOATE,MESYLATE
Nafamstat
Nafamostat
6-carbamimidoylnaphthalen2-yl 4-(diaminomethyleneamino) benzoate
FUT-175
6-Amidino-2-naphthyl 4-guanidinobenzoate
NafamostatMesilateBase
4-[(Aminoiminomethyl)amino]benzoic Acid 6-(Aminoiminomethyl)-2-naphthalenyl Ester
4-Guanidinobenzoic acid 6-amidino-2-naphtyl ester



2. Packaging

For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.

For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product. 

                     Or smaller package 1kg/bottle, 10kgs/bottle as request. 


Article illustrationArticle illustration


3. Shipping

Article illustration


4. Contact information

For more details, pls contact us freely.

Email address : sun@fdachem.com

Mob: 86 13526505137

WhatsApp/Skype/Wechat/LINE: 86 13526505137





Company Profile Introduction

Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.

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  • Since: 2023-02-10
  • Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro
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