Product Details
| Product Name:
(-)-Anonaine |
CAS No.:
1862-41-5 |
| Purity:
99.60% |
Supply Ability:
10g |
| Release date:
2024/11/18 |
Product Introduction
Bioactivity
| Name | (-)-Anonaine |
| Description | (-)-Anonaine can be extracted from several species of Magnoliaceae and Annelidae and has antimalarial, antibacterial, antifungal, antioxidant, anticancer, antidepressant and vasodilatory activities. (-)-Anonaine induces apoptosis in human cervical cancer (HeLa) cells, induces DNA damage and inhibits the growth and migration of human lung cancer h1299 cells through Bax and caspase-dependent pathways. |
| In vitro | (-)-Anonaine (50-200 μM ; 24h ; ) exhibited significant inhibition to cell growth and migration activities on human lung cancer H1299 cells.[1]
(-)-Anonaine (10-200 μM) significant nuclear damages of H1299 cells were observed treatment in a comet assay, whereas higher concentrations (6 and 30 mM) of (-)-anonaine concentrations were required to cause DNA damages in an in vitro plasmid cleavage assay.[1] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 2.65 mg/mL (10 mM)
|
| Keywords | ( ) Anonaine | ()Anonaine | Anonaine |
| Inhibitors Related | Stavudine | Dehydroacetic acid sodium | 5-Fluorouracil | Sodium 4-phenylbutyrate | L-Ascorbic acid | Hydroxychloroquine | Doxycycline | Tributyrin | Geraniol | L-Cystine |
| Related Compound Libraries | 抗寄生蟲庫 | 中藥單體化合物庫 | 經(jīng)典已知活性庫 | 生物堿類天然產(chǎn)物庫 | 植物來源化合物庫 | 抗真菌庫 | 抗寄生蟲天然產(chǎn)物庫 | 抗感染天然產(chǎn)物庫 | 已知活性化合物庫 | 藥食同源庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |
United States