3-(4-Phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine
Price | Get Latest Price | ||
Package | 1kg | 10kg | 25kg |
Min. Order: | 1kg |
Supply Ability: | 5000kg |
Update Time: | 2024-12-26 |
Product Details
Product Name: 3-(4-Phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine | CAS No.: 330786-24-8 |
Min. Order: 1kg | Purity: 99%min |
Supply Ability: 5000kg | Release date: 2024/12/26 |
5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine, also known as ibrutinib N-2, is a light brown solid. It can be prepared from 3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine and 4-phenoxybenzeneboronicacid by Suzuki coupling reaction[1]. Ibrutinib N-2 is often used in the preparation of the marketed drug PCI-32765 (IMBRUVICAVR)[2]. PCI-32765 is aIbrutinib -BTK inhibitor and can be used as an anticancer drug to treat B cell cancers like mantle cell lymphoma and chronic lymphocytic leukemia.
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- Since: 2011-07-26
- Address: Shandong Jinan, China
15562555968
info@pharmachemm.com