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Xi'an Confluore Biological Technology Co., Ltd.
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Product Name:Bis-sulfone-PEG4-NHS ester CAS:2055047-19-1 Purity:98% HPLC Package:10MG;25MG;50MG;100MG;1G;5G Remarks:For customers outside China,please use the website:www.confluore.com
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4,7,10,13-Tetraoxa-16-azaheptadecanoic acid, 17-[4-[3-[(4-methylphenyl)sulfonyl]-2-[[(4-methylphenyl)sulfonyl]methyl]-1-oxopropyl]phenyl]-17-oxo-, 2,5-dioxo-1-pyrrolidinyl ester manufacturers
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| 4,7,10,13-Tetraoxa-16-azaheptadecanoic acid, 17-[4-[3-[(4-methylphenyl)sulfonyl]-2-[[(4-methylphenyl)sulfonyl]methyl]-1-oxopropyl]phenyl]-17-oxo-, 2,5-dioxo-1-pyrrolidinyl ester Basic information |
Product Name: | 4,7,10,13-Tetraoxa-16-azaheptadecanoic acid, 17-[4-[3-[(4-methylphenyl)sulfonyl]-2-[[(4-methylphenyl)sulfonyl]methyl]-1-oxopropyl]phenyl]-17-oxo-, 2,5-dioxo-1-pyrrolidinyl ester | Synonyms: | 4,7,10,13-Tetraoxa-16-azaheptadecanoic acid, 17-[4-[3-[(4-methylphenyl)sulfonyl]-2-[[(4-methylphenyl)sulfonyl]methyl]-1-oxopropyl]phenyl]-17-oxo-, 2,5-dioxo-1-pyrrolidinyl ester;Bis-sulfone-PEG4-NHS Ester | CAS: | 2055047-19-1 | MF: | C40H48N2O14S2 | MW: | 844.94 | EINECS: | | Product Categories: | | Mol File: | 2055047-19-1.mol | |
| 4,7,10,13-Tetraoxa-16-azaheptadecanoic acid, 17-[4-[3-[(4-methylphenyl)sulfonyl]-2-[[(4-methylphenyl)sulfonyl]methyl]-1-oxopropyl]phenyl]-17-oxo-, 2,5-dioxo-1-pyrrolidinyl ester Chemical Properties |
density | 1.38±0.1 g/cm3(Predicted) | solubility | Soluble in DMSO, DCM, DMF | pka | 13.33±0.46(Predicted) |
| 4,7,10,13-Tetraoxa-16-azaheptadecanoic acid, 17-[4-[3-[(4-methylphenyl)sulfonyl]-2-[[(4-methylphenyl)sulfonyl]methyl]-1-oxopropyl]phenyl]-17-oxo-, 2,5-dioxo-1-pyrrolidinyl ester Usage And Synthesis |
Description | Bis-sulfone-PEG4-NHS Ester is a bis-alkylating labeling reagent that is selective for the cysteine sulfur atoms from a native disulfide. These reagents undergo bis-alkylation to conjugate both thiols derived from the two cysteine residues of a reduced native disulfide bond such as the interchain disulfide bonds of an antibody. The reaction results in covalent rebridging of the disulfide bond via a three carbon bridge leaving the protein structurally intact. The hydrophilic PEG spacer increases solubility in aqueous media. |
| 4,7,10,13-Tetraoxa-16-azaheptadecanoic acid, 17-[4-[3-[(4-methylphenyl)sulfonyl]-2-[[(4-methylphenyl)sulfonyl]methyl]-1-oxopropyl]phenyl]-17-oxo-, 2,5-dioxo-1-pyrrolidinyl ester Preparation Products And Raw materials |
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