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| | 2-nitro-4-Bromo-5-fluorobenzoic acid Basic information |
| | 2-nitro-4-Bromo-5-fluorobenzoic acid Chemical Properties |
| Boiling point | 367.6±42.0 °C(Predicted) | | density | 1.967±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | pka | 1.68±0.25(Predicted) | | form | crystalline powder | | color | Off-white |
| | 2-nitro-4-Bromo-5-fluorobenzoic acid Usage And Synthesis |
| Uses |
2-nitro-4-Bromo-5-fluorobenzoic acid is an important intermediate for the synthesis of a new generation of fluoroquinolone drugs represented by ciprofloxacin.
| | Synthesis |
2,4-Dibromo-5-fluorotoluene was brominated with NBS, hydrolyzed in acid to form aldehyde, and then oxidized by Jones reagent to obtain 2-nitro-4-Bromo-5-fluorobenzoic acid.
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| | 2-nitro-4-Bromo-5-fluorobenzoic acid Preparation Products And Raw materials |
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