(9E)-9-十六烯酸
| 中文名稱(chēng) | (9E)-9-十六烯酸 |
|---|---|
| 中文同義詞 | (9E)-9-十六烯酸;反式-9-十六碳烯酸;十六碳烯酸(反-9);反式-棕櫚油酸;棕櫚酸酯?;(E)-9-十六烯酸;十六碳烯酸(反-9)/反棕櫚油酸 |
| 英文名稱(chēng) | PALMITELAIDIC ACID |
| 英文同義詞 | (9E)-9-Hexadecenoicacid;(e)-9-hexadecenoicaci;TRANS-9-HEXADECENOIC ACID;C16:1 (TRANS-9) ACID;DELTA 9 TRANS HEXADECENOIC ACID;PALMITELAIDIC ACID 99%;(E)-9-Hexadecenoicacid;9-Hexadecenoic acid, (9E)- |
| CAS號(hào) | 10030-73-6 |
| 分子式 | C16H30O2 |
| 分子量 | 254.41 |
| EINECS號(hào) | |
| 相關(guān)類(lèi)別 | 脂肪酸 |
| Mol文件 | 10030-73-6.mol |
| 結(jié)構(gòu)式 |  |
(9E)-9-十六烯酸 性質(zhì)
| 熔點(diǎn) | 33-34℃ |
|---|---|
| 沸點(diǎn) | 374.4°C (estimate) |
| 密度 | 0.8855 (rough estimate) |
| 折射率 | 1.4501 (589.3 nm 40℃) |
| 儲(chǔ)存條件 | Amber Vial, Refrigerator |
| 溶解度 | 可溶于DMSO（少量）、甲醇（少量） |
| 酸度系數(shù)(pKa) | 4.78±0.10(Predicted) |
| 形態(tài) | 液體 |
| 顏色 | 白色至類(lèi)白色 |
| LogP | 6.635 (est) |
| EPA化學(xué)物質(zhì)信息 | 9-Hexadecenoic acid, (9E)- (10030-73-6) |
|
AMPK
|
PPARα
|
Glucokinase
|
The monounsaturated fatty acid palmitoleate (palmitoleic acid) is one of the most abundant fatty acids in serum and tissues, particularly adipose tissue and liver. Its endogenous production by stearoyl-CoA desaturase 1 gives rise to its cis isoform, cis-palmitoleate. Palmitoleic acid has been correlated with multiple cardiometabolic risk factors, including high blood pressure, total cholesterol, TGs, apoA-I, apoB, and endothelial dysfunction.
Palmitoleic acid promotes a faster uptake of glucose in the body, associated with higher insulin concentration. Palmitoleic acid increases the phosphorylation of AMPK, up-regulates glucokinase and down-regulates SREBP-1. Regarding AMPK downstream, palmitoleic acid increases the production of FGF-21 and stimulates the expression of PPARα. Palmitoleic acid reduces body weight increase, ameliorates the development of hyperglycemia and hypertriglyceridemia, and improves insulin sensitivity. Furthermore, palmitoleic acid down-regulates mRNA expressions of proinflammatory adipocytokine genes (TNFα and resistin) in white adipose tissue and lipogenic genes (SREBP-1, FAS, and SCD-1) in liver.
安全信息
| 更新日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱(chēng) | CAS號(hào) | 包裝 | 價(jià)格 |
|---|---|---|---|---|---|
| 2024/11/08 | HY-N2341 | (9E)-9-十六烯酸 Palmitelaidic Acid | 10030-73-6 | 10mg(393mM * 100μL in Ethanol) | 500元 |
| 2024/11/08 | HY-N2341 | Palmitelaidic Acid | 25 mg (393 mM * 250 μL in Ethanol) | 1000元 |