4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl

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Company Name:	TargetMol Chemicals Inc.
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Products Intro:	Product Name:Pomalidomide-C3-NH2 hydrochloride CAS:2154342-45-5 Purity:99.60% Package:2mg;37USD\|5mg;59USD\|10mg;89USD

Company Name:	Nextpeptide Inc
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Products Intro:	Product Name:4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl CAS:2154342-45-5 Purity:98% Min. Package:5KG;1KG

Company Name:	TargetMol Chemicals Inc.
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Products Intro:	Product Name:Pomalidomide-C3-NH2 hydrochloride CAS:2154342-45-5 Package:10 mg；2 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY

Company Name:	Xian confluore Biological Technology Co., Ltd.
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Products Intro:	Product Name:Pomalidomide-C3-NH2 hydrochloride CAS:2154342-45-5 Purity:>99.00% Package:100mg

Company Name:	Aladdin Scientific
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Products Intro:	Product Name:Pomalidomide 4'-alkylC3-amine hydrochloride CAS:2154342-45-5 Purity:>=95%(HPLC) Package:$65.9/5mg;$100.9/10mg;$192.9/25mg;$347.9/50mg;$624.9/100mg;Bulk package Remarks:95%(HPLC)

4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl manufacturers

4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Basic information

Product Name:	4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
Synonyms:	4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl;4-((3-Aminopropyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride;4-[(3-aminopropyl)amino]-2-(2,6-dioxopiperidin-3- yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride;Thalidomide-NH-C4-NH2 HCl;Inhibitor,E3 Ligase Ligand-Linker Conjugates,inhibit,Pomalidomide C3 NH2 hydrochloride,Pomalidomide-C-3-NH2 hydrochloride,PomalidomideC3NH2 hydrochloride;Pomalidomide 4'-alkylC3-amine hydrochloride;Poma-C3-NH2·HCl;Pomalidomide-C3-amine HCl
CAS:	2154342-45-5
MF:	C16H19ClN4O4
MW:	366.79946
EINECS:
Product Categories:
Mol File:	2154342-45-5.mol

4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Chemical Properties

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MSDS Information

4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Usage And Synthesis

Uses	Pomalidomide-C3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1].
IC 50	Cereblon
storage	Store at -20°C
References	[1] Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine.?Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. DOI:10.3389/fcell.2021.629326 [2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277

4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Preparation Products And Raw materials

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