3-酮基-7ALPHA,12ALPHA-二羥基-5ALPHA-膽烷酸
| 中文名稱 | 3-酮基-7ALPHA,12ALPHA-二羥基-5ALPHA-膽烷酸 |
|---|---|
| 中文同義詞 | 3-酮基-7ALPHA,12ALPHA-二羥基-5ALPHA-膽烷酸;3-酮基-7Α,12Α-二羥基-5Α-膽烷酸;3,脫氫膽酸;3-氧代-7A,12A-二羥基-5B-膽烷酸;3-氧代脫氧膽酸;膽酸雜質(zhì)19;3-氧脫氧膽酸;化合物3-?OXOCHOLIC ACID |
| 英文名稱 | 4-(7,12-dihydroxy-10,13-dimethyl-3-oxo-1,2,4,5,6,7,8,9,11,12,14,15,16,17-te tradecahydrocyclopenta[a]phenanthren-17-yl)pentanoic acid |
| 英文同義詞 | 3-Oxocholic acid;4-(7,12-dihydroxy-10,13-dimethyl-3-oxo-1,2,4,5,6,7,8,9,11,12,14,15,16,17-te tradecahydrocyclopenta[a]phenanthren-17-yl)pentanoic acid;7,12-dihydroxy-3-oxocholanic acid;3-Oxo-7α,12α-dihydroxy-5β-cholan-24-oic acid;3-Oxo-7α,12α-dihydroxycholanic acid;7α,12α-Dihydroxy-3-oxo-5β-cholanic acid;3-Oxo-7α,12α-hydroxy-5β-cholanoic Acid;3-Oxo Deoxycholic Acid |
| CAS號 | 2304-89-4 |
| 分子式 | C24H38O5 |
| 分子量 | 406.56 |
| EINECS號 | |
| 相關類別 | |
| Mol文件 | 2304-89-4.mol |
| 結構式 |  |
3-酮基-7ALPHA,12ALPHA-二羥基-5ALPHA-膽烷酸 性質(zhì)
| 熔點 | 185 °C |
|---|---|
| 沸點 | 583.0±50.0 °C(Predicted) |
| 密度 | 1.180±0.06 g/cm3(Predicted) |
| 儲存條件 | 2-8°C |
| 溶解度 | 可溶于氯仿（輕微，加熱），甲醇（輕微） |
| 形態(tài) | 固體 |
| 酸度系數(shù)(pKa) | 4.76±0.10(Predicted) |
| 顏色 | 灰白色至淺米色 |
| 穩(wěn)定性 | 吸濕性 |
3-Oxocholic acid 是一種氧膽汁酸的代謝產(chǎn)物，也是產(chǎn)氣莢膜梭菌在腸道中由膽汁產(chǎn)生的主要降解產(chǎn)物。3-Oxocholic acid 是一種類固醇酸，主要存在于哺乳動物的膽汁中。
Male Goto-Kakizaki (GK) rats rats are subjected to Ileal transposition (IT) surgery. In the metabolomics analysis, compared with Sham-IT rats, 3-Oxocholic acid of IT rats is increased.