Company Name: |
Shanghai Biobond Pharmaceutical Co.,Ltd.
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Tel: |
21-68719686 18917373795 |
Email: |
sales@sh-biobond.cn |
Products Intro: |
Product Name:Cholesterol probe for Smoothened CAS:2106868-12-4 Purity:98% H-NMR Package:10 mg; 20 mg; 100 mg
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Company Name: |
Shanghai Keke Biotechnology Co., Ltd.
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Tel: |
021-34975789 18721102763 |
Email: |
click@click-biotech.com |
Products Intro: |
Product Name:Cholesterol probe for Smoothened CAS:2106868-12-4 Purity:95%+ Package:5mg;10mg;25mg
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| Cholesterol probe for Smoothened Basic information |
| Cholesterol probe for Smoothened Chemical Properties |
| Cholesterol probe for Smoothened Usage And Synthesis |
Uses | Chol-N3 is a bioorthogonal-based chol probe. Chol-N3 can combine with super-resolution fluorescence microscopy (SRM), providing direct visualization of nanoscale lipid heterogeneity in the cell surface of resting living cells[1]. Chol-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | References | [1] Lorizate M, et, al. Super-Resolution Microscopy Using a Bioorthogonal-Based Cholesterol Probe Provides Unprecedented Capabilities for Imaging Nanoscale Lipid Heterogeneity in Living Cells. Small Methods. 2021 Sep;5(9):e2100430. DOI:10.1002/smtd.202100430 |
| Cholesterol probe for Smoothened Preparation Products And Raw materials |
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