- Demethyleneberberine
-
- $1400.00 / 1g
-
2024-11-28
- CAS:25459-91-0
- Min. Order: 1g
- Purity: 98
- Supply Ability: 50 Kg
- Demethyleneberberine
-
- $61.00 / 1mg
-
2024-11-19
- CAS:25459-91-0
- Min. Order:
- Purity: 99.18%
- Supply Ability: 10g
- Demethyleneberberine
-
- $0.00 / 10mg
-
2023-02-24
- CAS:25459-91-0
- Min. Order: 10mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
|
| | DeMethyleneberberine Basic information |
| Product Name: | DeMethyleneberberine | | Synonyms: | DeMethyleneberberine;Dibenzo[a,g]quinoliziniuM,5,6-dihydro-2,3-dihydroxy-9,10-diMethoxy;9,10-dimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-2,3-diol;2,3-dihydroxy-9,10-dimethoxy-5,6-dihydroisoquino[3,2-a]isoquinolinium;2,3-dihydroxy-9,10-dimethoxy-5,6-dihydroisoquinolino[3,2-a]isoquinolin-7-ium;DeMethyleneberberine USP/EP/BP;2,3-dihydroxy-9,10-dimethoxy-5,6-dihydroisoquino[3,2-a]isoqu...;Demethyleneberberine, 10 mM in DMSO | | CAS: | 25459-91-0 | | MF: | C19H18NO4+ | | MW: | 324.36 | | EINECS: | | | Product Categories: | Alkaloids;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;chemical reagent;pharmaceutical intermediate;phytochemical | | Mol File: | 25459-91-0.mol |  |
| | DeMethyleneberberine Chemical Properties |
| storage temp. | 4°C, protect from light | | solubility | DMSO : 33.33 mg/mL (102.76 mM; Need ultrasonic) | | form | powder | | color | Yellow |
| | DeMethyleneberberine Usage And Synthesis |
| Uses | Demethyleneberberine is a naturally occurring alkaloid in plants that displays anti-adipogenic effects and is also shown to alleviate IBS. | | Biological Activity | Demethyleneberberine, a berberine metabolite, is a mitochondria-targeted antioxidant isolated from Cortex Phellodendri chinensis th at exhibits multiple pharmacological activities including anti-microbial, anti-inflammatory, anti-diarrhea and anti-cancer. Demethyleneberberine alleviates ethanol-dependent oxidative stress by suppression of cytochrome CYP2E1 (P450 2E1), hypoxia inducible factor α (HIF-1α) and inducible nitric oxide synthase (iNOS). It appears th at demethyleneberberine attenuates non-alcoholic fatty liver disease (NAFLD) through activation of AMPK. | | target | P450 (e.g. CYP17) | HIF | NOS |
| | DeMethyleneberberine Preparation Products And Raw materials |
|