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Product Name:Altenusin
CAS:31186-12-6
Purity:>=98% Remarks:Reach out to us for more information about custom solutions.
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altenusin manufacturers
- Altenusin
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- $389.00 / 1mg
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2024-11-19
- CAS:31186-12-6
- Min. Order:
- Purity: 98.97%
- Supply Ability: 10g
- altenusin
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- $1.00 / 1Kg
-
2024-07-20
- CAS:31186-12-6
- Min. Order: 1Kg
- Purity: 98%
- Supply Ability: 20T
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| | altenusin Basic information |
| Product Name: | altenusin | | Synonyms: | altenusin;Altenusin, Penicillium sp.;[1,1'-Biphenyl]-2-carboxylic acid, 3,4',5'-trihydroxy-5-methoxy-2'-methyl-;Alutenusin;inhibit,Altenusin,Alutenusin,Inhibitor | | CAS: | 31186-12-6 | | MF: | C15H14O6 | | MW: | 290.27 | | EINECS: | | | Product Categories: | | | Mol File: | 31186-12-6.mol |  |
| | altenusin Chemical Properties |
| Melting point | 202-203 °C(Solv: chloroform (67-66-3)) | | Boiling point | 491.8±45.0 °C(Predicted) | | density | 1.431±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: soluble; Ethanol: soluble; Methanol: soluble | | form | A solid | | pka | 3.08±0.34(Predicted) | | color | Yellow | | biological source | Penicillium sp. |
| | altenusin Usage And Synthesis |
| Uses | Altenusin is an antifungal penicillide and strong pp60c-Src inhibitor. | | Definition | ChEBI: Altenusin is a carboxybiphenyl that is [biphenyl]-2-carboxylic acid which is substituted by a hydroxy group at positions 3, 4' and 5', methoxy group at position 5 and a methyl group at position 2'. It is a a metabolite isolated from Alternaria and several other fungal species. It has a role as an antifungal agent and a fungal metabolite. It is a polyphenol, a carboxybiphenyl, an aromatic ether, a member of hydroxybiphenyls and a member of catechols. | | Biological Activity | Altenusin, a non-steroidal fungal metabolite, is a potent and selective agonist of Farnesoid X receptor (FXR) th at protects mice from high-f at diet induced obesity. Also it decreases blood glucose level, serum insulin level, and reduces lipid droplets accumulation. Altenusin inhibits trypanothione reductase from Trypanosoma cruzi. | | storage | +4°C |
| | altenusin Preparation Products And Raw materials |
| Raw materials | Boronic acid, [4,5-bis(methoxymethoxy)-2-methylphenyl]- (9CI)-->4H-1,3-Benzodioxin-4-one, 7-methoxy-2,2-dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)--->1,3-Benzodioxole, 5-iodo-6-methyl--->4,4,5,5-tetramethyl-2-(6-methylbenzo[d][1,3]dioxol-5-yl)-1,3,2-dioxaborolane-->1,2-Benzenediol, 4-bromo-5-methyl- (9CI)-->5 7-DIHYDROXY-2 2-DIMETHYL-4H-1 3-BENZO&-->TrifluoroMethanesulfonic Acid 7-Methoxy-2,2-diMethyl-4-oxo-4H-1,3-benzodioxin-5-yl Ester-->5-Hydroxy-7-Methoxy-2,2-diMethyl-4H-1,3-benzodioxin-4-one-->2,4,6-Trihydroxybenzoic acid |
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