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Amatek Scientific Co. Ltd.
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Product Name:1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]amino]- CAS:2140807-36-7 Purity:97% HPLC Package:5g;25g;100g;1kg
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1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]amino]- manufacturers
- Pomalidomide-PEG3-OH
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- $89.00 / 1mg
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2024-11-19
- CAS:2140807-36-7
- Min. Order:
- Purity: 99.65%
- Supply Ability: 10g
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| 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]amino]- Basic information |
Product Name: | 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]amino]- | Synonyms: | 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]amino]-;2-(2,6-dioxopiperidin-3-yl)-4-((2-(2-(2-hydroxyethoxy)ethoxy)ethyl)amino)isoindoline-1,3-dione;Pomalidomide-NH-PEG2-OH;6-dioxo-3-piperidinyl)-4-[[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]amino]-;Pomalidomide-PEG3-OH;Pomalidomide-PEG-3-OH,Pomalidomide PEG3 OH,PomalidomidePEG3OH;2-(2,6-dioxopiperidin-3-yl)-4-({2-[2-(2-hydroxyethoxy)ethoxy]ethyl}amino)-2,3-dihydro-1H-isoindole-1,3-dione;Pomalidomide-PEG3-OH | CAS: | 2140807-36-7 | MF: | C19H23N3O7 | MW: | 405.4 | EINECS: | | Product Categories: | | Mol File: | 2140807-36-7.mol | ![1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]amino]- Structure](CAS/20210305/GIF/2140807-36-7.gif) |
| 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]amino]- Chemical Properties |
Boiling point | 689.8±55.0 °C(Predicted) | density | 1.427±0.06 g/cm3(Predicted) | storage temp. | 2-8°C | pka | 10.74±0.40(Predicted) | form | powder |
| 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]amino]- Usage And Synthesis |
Uses | Pomalidomide-PEG3-OH (compound 53b) is an E3 Ligase Ligand-Linker Conjugates consisting of a pomalidomide (HY-10984)-based cereblon ligand and a 3-unit PEG linker[1]. | IC 50 | Cereblon | References | [1] Zhang X, Thummuri D, Liu X, Hu W, Zhang P, Khan S, Yuan Y, Zhou D, Zheng G. Discovery of PROTAC BCL-XL degraders as potent anticancer agents with low on-target platelet toxicity. Eur J Med Chem. 2020 Apr 15;192:112186. DOI:10.1016/j.ejmech.2020.112186 |
| 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]amino]- Preparation Products And Raw materials |
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