- Dendrophenol
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- $106.00 / 1mg
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2025-04-27
- CAS:108853-14-1
- Min. Order:
- Purity: 98.96%
- Supply Ability: 10g
- Dendrophenol
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- $9.80 / 1KG
-
2020-02-07
- CAS:108853-14-1
- Min. Order: 1KG
- Purity: ＞98%HPLC
- Supply Ability: 20 tons
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| | dendrophenol Basic information |
| Product Name: | dendrophenol | | Synonyms: | dendrophenol;Aloifol II;Moscatilin;4-[2-(4-Hydroxy-3-methoxyphenyl)ethyl]-2,6-dimethoxy-phenol;4-(4-hydroxy-3-methoxyphenethyl)-2,6-dimethoxyphenol;Gigantol(Dendrophenol);Phenol,4-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-2,6-dimethoxy-;4，4'-Dihydroxy-3，3'，5-trimethoxybibenzyl | | CAS: | 108853-14-1 | | MF: | C17H20O5 | | MW: | 304.34 | | EINECS: | 300-009-3 | | Product Categories: | | | Mol File: | 108853-14-1.mol |  |
| | dendrophenol Chemical Properties |
| Melting point | 87-89℃ (ethyl ether ) | | Boiling point | 454.1±40.0 °C | | density | 1.208±0.06 g/cm3 (20 ºC 760 Torr) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 10.09±0.20(Predicted) | | form | Solid | | color | White to off-white |
| | dendrophenol Usage And Synthesis |
| Uses | Dendrophenol can be used to protect against high glucose-evoked nephrotoxicity in vivo. It can be used with HPLC-PDA-HRMS-SPE-NMR for determination of its inhibitive activities. | | in vivo | Dendrophenol (10 mg/kg; intraperitoneal injection; 3 weeks) has a beneficial effect in the mouse model of vascular calcification[3].
Dendrophenol (50-100 mg/kg; intraperitoneal injection; 5 times a week for 2 weeks) has antitumor effect in mouse tumor model[4]. | Animal Model: | Nicotine and Vitamin D3 (HY-15398) treated male C57BL/6J mice aged 25 weeks old[3] | | Dosage: | 10 mg/kg | | Administration: | Intraperitoneal injection (i.p.); 3 weeks | | Result: | Reduced calcium accumulation in the thoracic aorta and aortic valves of the mice.
Reduced the expression of calcification-related genes, such as ALPL, BMP2 and RUNX2.
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| Animal Model: | HCT-116 cells treated male severe combined immunodeficient mice[4] | | Dosage: | 50 and 100 mg/kg | | Administration: | Intraperitoneal injection (i.p.); five times a week for two weeks | | Result: | Significantly inhibited tumor growth and did not result in weight loss.
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| | IC 50 | NF-κB; COX-2; HIF-1α |
| | dendrophenol Preparation Products And Raw materials |
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