- 6-Amino-1-hexanol
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- $0.00 / 1KG
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2022-09-07
- CAS:4048-33-3
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1Ton
- 6-Amino-1-hexanol
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- $1.00 / 1KG
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2019-07-06
- CAS:4048-33-3
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: Customized
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| | 6-Amino-1-hexanol Basic information |
| | 6-Amino-1-hexanol Chemical Properties |
| Melting point | 54-58 °C (lit.) | | Boiling point | 135-140 °C/30 mmHg (lit.) | | density | 0.8872 (estimate) | | refractive index | 1.4444 (estimate) | | Fp | 133 °C | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | DMSO (Slightly), Chloroform (Slightly), Methanol (Slightly) | | form | Crystals | | pka | 15.18±0.10(Predicted) | | color | Light yellow to brown | | Water Solubility | MISCIBLE | | Sensitive | Hygroscopic | | BRN | 1732524 | | Stability: | Hygroscopic. Stable. Incompatible with strong oxidizing agents. | | InChIKey | SUTWPJHCRAITLU-UHFFFAOYSA-N | | CAS DataBase Reference | 4048-33-3(CAS DataBase Reference) | | NIST Chemistry Reference | NH2(CH2)6OH(4048-33-3) | | EPA Substance Registry System | 1-Hexanol, 6-amino- (4048-33-3) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-37/39-36 | | WGK Germany | 3 | | RTECS | MO8840000 | | F | 3-10 | | HazardClass | IRRITANT, HYGROSCOPIC | | HS Code | 29221990 |
| | 6-Amino-1-hexanol Usage And Synthesis |
| Chemical Properties | slightly yellow crystalline powder | | Uses | 6-Amino-1-hexanol can undergo cyclization over copper supported on γ-alumina and magnesia to form hexahydro-1H-azepine. It may be used along with glutaric acid to generate poly(ester amide)s with excellent film- and fiber forming properties. | | Uses | 6-Amino-1-hexanol is used as pharmaceutical intermediate. | | Uses | 6-Amino-1-hexanol is used in the synthesis of guanidino analogs of roscovitine, which is a cyclin-dependant kinase. Also used in the preparation of tocotrienols which maintain anticancer, antiprolifer
ative and antimigratory activity. Behery, F | | Synthesis |
By volume ratio, 1 part of 6-aminohexanoic acid was added to the reactor containing 15 parts of diethyl ether or dry toluene solution At 40 ℃ constant temperature, At 1500rpm / min speed, rapidly injected 2 parts of a solution of sodium borohydride. At 250W, ultrasonic treatment 20min. Then, dropwise under reflux, 8 parts of ethylene glycol solution. Dropwise addition time was 30 minutes. Finally, at 90 ℃ and at a rate of 800rpm/min, maintain temperature under stirring and react for 16 h to obtain the reaction crude product. (2) By the amount of parts count, step (1) preparation of 1 part of the reaction crude was added 6 parts water for hydrolysis. Undrego vacuum distillation, collecting 125 ℃ fraction, to obtain the 6-amino-1-hexanol product.
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| | 6-Amino-1-hexanol Preparation Products And Raw materials |
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