ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT
生物活性靶點體外研究體內(nèi)研究 用途與合成方法 MSDS ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT價格(試劑級) 上下游產(chǎn)品信息
| 中文名稱 | ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT |
|---|---|
| 中文同義詞 | RP-CAMPS 鈉鹽;ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT |
| 英文名稱 | ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT |
| 英文同義詞 | SP-CYCLIC 3,5-HYDROGEN PHOSPHOROTHIOATE ADENOSINE SODIUM SALT;RP-CAMPS NA;RP-CAMPS SODIUM SALT;ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT;ADENOSINE 3',5'-CYCLIC MONOPHOSPHOTHIOATE, RP-ISOMER SODIUM SALT;CAMPS NA RP-ISOMER;Rp cAMPS sodium salt,RpcAMPS sodium salt;Rp-cAMPS sodium |
| CAS號 | 142439-94-9 |
| 分子式 | C10H13N5NaO5PS |
| 分子量 | 369.27 |
| EINECS號 | |
| 相關(guān)類別 | |
| Mol文件 | Mol File |
| 結(jié)構(gòu)式 |  |
ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT 性質(zhì)
| 儲存條件 | Store at -20°C, sealed storage, away from moisture and light |
|---|---|
| 形態(tài) | 固體 |
| 顏色 | 白至粉紅 |
Rp-cAMPS sodium salt，一種 cAMP 的類似物，是一種 cAMP 誘導(dǎo)的 PKA I 和 PKA II 活化 (Ki 分別為 12.5 μM 和 4.5 μM) 的有效的，競爭性拮抗劑。Rp-cAMPS sodium salt 耐磷酸二酯酶水解。
Ki: 6.05 μM (PKA I) and 9.75 μM (PKA II)
A membrane-permeable competitive cAMP antagonist (Rp-cAMPS) that blocks PKA activation by binding to the regulatory subunits without dissociating the kinase holoenzyme also inhibits synaptic plasticity but has no effect on normal synaptic transmission.
Rp-cAMPS (10 μM, 15 min) decreases the monosynaptic EPSCs evoked at the PB-CeLC and BLA-CeLC synapses in slices from arthritic rats but not in control neurons from normal animals. The inhibitory effect of Rp-cAMPS is significant compared to predrug (ACSF) control values obtained in the same neurons.
安全信息
| 更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
|---|---|---|---|---|---|
| 2025/02/08 | HY-100530D | ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT Rp-cAMPS sodium salt | 142439-94-9 | 1mg | 1800元 |
| 2025/02/08 | HY-100530D | ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT Rp-cAMPS sodium salt | 142439-94-9 | 10 mM * 1 mLin Water | 4040元 |