- Elemicin
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- $41.00 / 100mg
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2024-11-14
- CAS:487-11-6
- Min. Order:
- Purity: 96.27%
- Supply Ability: 10g
- Elemicin
-
- $9.00 / 1KG
-
2024-01-08
- CAS:487-11-6
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50000tons
- Elemicin
-
- $140.00 / 1KG
-
2023-08-16
- CAS:487-11-6
- Min. Order: 1KG
- Purity: >99%
- Supply Ability: 50000kg/Month
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| | Elemicin Basic information |
| Product Name: | Elemicin | | Synonyms: | ELIMICIN;ELEMICIN;1,2,3-trimethoxy-5-(2-propenyl)-benzen;1,2,3-trimethoxy-5-allylbenzene (elemicin);3,4,5-Trimethoxyallylbenzene;4-allyl-1,2,6-trimethoxybenzene;5-allyl-1,2,3-trimethoxy-benzen;Benzene, 5-(2-propenyl)-1,2,3-trimethoxy | | CAS: | 487-11-6 | | MF: | C12H16O3 | | MW: | 208.25 | | EINECS: | 207-649-0 | | Product Categories: | Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 487-11-6.mol |  |
| | Elemicin Chemical Properties |
| Boiling point | 152-156 °C | | density | 1.0630 g/cm3 | | storage temp. | Amber Vial, -20°C Freezer | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) | | form | Oil | | color | Colourless | | Odor | at 100.00 %. spice flower | | Odor Type | spicy | | Stability: | Light Sensitive | | LogP | 2.298 (est) | | NIST Chemistry Reference | Benzene, 1,2,3-trimethoxy-5-(2-propenyl)-(487-11-6) |
| | Elemicin Usage And Synthesis |
| Description | Elemicin is a trioxygenated phenylpropane that has been found in A. dracunculus. It is active against S. aureus, B. subtilis, and C. albicans (MICs = 600, 2,500, and 1,000 mg/L, respectively) but not E. coli, K. pneumoniae, P. aeruginosa (MICs = >8,000 mg/L for all), or L. monocytogenes (MIC = >3,000 mg/L). Elemicin is toxic to mice following metabolic activation to 1’-hydroxyelemicin by the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2. It increases plasma and hepatic triglyceride levels, decreases stearoyl-CoA desaturase 1 (Scd1) expression, and induces hepatomegaly in mice when administered at a dose of 500 mg/kg per day for three weeks. | | Chemical Properties | Clear Colorless Oil | | Uses | A constituent of the essential oil of nutmeg and is responsible for the psychoactive effects of nutmeg. Also a minor constituent of the oleoresin and essential oil of Manila elemi (Canarium luzonicum). Exhibits anticholinergic-like effects in humans. | | Definition | ChEBI: Elemicin is an olefinic compound. | | Synthesis | Prod. :
1) by isolation from Elemi oil (high-boiling
fractions).
2) from Dimcthylpyrogallol plus Allyl bromide,
via 2,6-Dimethyl pyrogallol allylether.
This is heated in a Claisen-rearrangement
reaction to yield 4-Hydroxy-3,5-dimethoxy
allylbenzene. The latter is methylated to
yield Elemicine.
3) From Eugenol via 5-Hydroxyeugenol. | | target | Antifection |
| | Elemicin Preparation Products And Raw materials |
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