(R)-(+)-6-羥基-2,5,7,8-四甲基色滿-2-羧酸
| 中文名稱 | (R)-(+)-6-羥基-2,5,7,8-四甲基色滿-2-羧酸 |
|---|---|
| 中文同義詞 | (R)-(+)-6-羥基-2,5,7,8-四甲基色滿-2-羧酸;(R)-(+)-6-羥基-2,5,7,8-四甲基色烷-2-羧酸;(R)-(+)-6-羥基-2,5,7,8-四甲基沒-2-羧酸;化合物 T12645;(R)-6-羥基-2,5,7,8-四甲基苯并二氫吡喃-2-羧酸;化合物 (R)-TROLOX |
| 英文名稱 | (R)-(+)-6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID |
| 英文同義詞 | (R)-(+)-6-hydroxy-2,5,7,8-tetramethyl-chroman-2-C;(2R)-2,5,7,8-Tetramethyl-6-hydroxychroman-2-carboxylic acid;(R)-3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid;(R)-Trolox;(R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid 98%;(2R)-6-Hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid;(R)-(+)-6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID;Trolox (R)-Isomer |
| CAS號(hào) | 53101-49-8 |
| 分子式 | C14H18O4 |
| 分子量 | 250.29 |
| EINECS號(hào) | |
| 相關(guān)類別 | Benzopyrans;Chiral Building Blocks;Heterocyclic Building Blocks |
| Mol文件 | 53101-49-8.mol |
| 結(jié)構(gòu)式 |  |
(R)-(+)-6-羥基-2,5,7,8-四甲基色滿-2-羧酸 性質(zhì)
| 熔點(diǎn) | 162 °C (dec.) (lit.) |
|---|---|
| 沸點(diǎn) | 450.3±45.0 °C(Predicted) |
| 密度 | 1.219±0.06 g/cm3(Predicted) |
| 儲(chǔ)存條件 | Store at -20°C |
| 溶解度 | 二甲基亞砜：250 mg/mL（998.84 mM） |
| 酸度系數(shù)(pKa) | 3.35±0.20(Predicted) |
| 形態(tài) | 固體 |
| 顏色 | 白色至米白色 |
| 旋光性 (optical activity) | [α]27/D +65°, c = 1.2 in ethanol |
(R)-Trolox 是水溶性維生素 E 類似物，是一種競(jìng)爭(zhēng)性酪氨酸酶抑制劑，Ki 值為 0.83 mM，ID50 值為 1.88 mM。(R)-Trolox 具有比 (S) 對(duì)映異構(gòu)體更強(qiáng)的酪氨酸酶親和力 (Ki 值為 0.61 mM)。
As compared to the control containing no inhibitor, DMSO suppresses the tyrosinase activity at tested levels, 100 and 200 μL in a total volume of 3.0 mL. The inhibition of DMSO on the mushroom tyrosinase is dosedependent. Additions of DMSO at the two levels in the tyrosinase digests containing (R)-Trolox ((R)-HTCCA) results in further inhibitions of the tyrosinase activity. The influence of the DMSO on the inhibitory effects of (R)-Trolox against the tyrosinase is also dose-dependent.
| 提供商 | 語(yǔ)言 |
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英文
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| 更新日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
|---|---|---|---|---|---|
| 2025/02/08 | HY-101445A | (R)-(+)-6-羥基-2,5,7,8-四甲基色滿-2-羧酸 (R)-Trolox | 53101-49-8 | 50mg | 510元 |
| 2025/02/08 | HY-101445A | (R)-(+)-6-羥基-2,5,7,8-四甲基色滿-2-羧酸 (R)-Trolox | 53101-49-8 | 10mM * 1mLin DMSO | 561元 |