ADRENOMEDULLIN (13-52) (HUMAN)
| 中文名稱 | ADRENOMEDULLIN (13-52) (HUMAN) |
|---|---|
| 中文同義詞 | 人腎上腺髓質(zhì)素(13-52);腎上腺髓質(zhì)素片段多肽13-52 |
| 英文名稱 | ADRENOMEDULLIN (13-52) (HUMAN) |
| 英文同義詞 | SER-PHE-GLY-CYS-ARG-PHE-GLY-THR-CYS-THR-VAL-GLN-LYS-LEU-ALA-HIS-GLN-ILE-TYR-GLN-PHE-THR-ASP-LYS-ASP-LYS-ASP-ASN-VAL-ALA-PRO-ARG-SER-LYS-ILE-SER-PRO-GLN-GLY-TYR-NH2: SFGCRFGTCTVQKLAHQIYQFTDKDKDNVAPRSKISPQGY-NH2DISULFIDE BRIDGE CYS16-CYS21;ADRENOMEDULLIN (13-52) (HUMAN);Ser-Phe-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2 (Disulfide bridge Cys16-Cys21);SFGCRFGTCTVQKLAHQIYQFTDKDKDNVAPRSKISPQGY-NH2 (DISULFIDE BRIDGE: 4-9);SER-PHE-GLY-CYS-ARG-PHE-GLY-THR-CYS-THR-VAL-GLN-LYS-LEU-ALA-HIS-GLN-ILE-TYR-GLN-PHE-THR-ASP-LYS-ASP-LYS-ASP-ASN-VAL-ALA-PRO-ARG-SER-LYS-ILE-SER-PRO-GLN-GLY-TYR-NH2;H-SER-PHE-GLY-CYS-ARG-PHE-GLY-THR-CYS-THR-VAL-GLN-LYS-LEU-ALA-HIS-GLN-ILE-TYR-GLN-PHE-THR-ASP-LYS-ASP-LYS-ASP-ASN-VAL-ALA-PRO-ARG-SER-LYS-ILE-SER-PRO-GLN-GLY-TYR-NH2;H-SER-PHE-GLY-CYS-ARG-PHE-GLY-THR-CYS-THR-VAL-GLN-LYS-LEU-ALA-HIS-GLN-ILE-TYR-GLN-PHE-THR-ASP-LYS-ASP-LYS-ASP-ASN-VAL-ALA-PRO-ARG-SER-LYS-ILE-SER-PRO-GLN-GLY-TYR-NH2 (DISULFIDE BRIDGE: 4-9);Adrenomedullin (13-52) (human) H-Ser-Phe-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2 (Disulfide bond) |
| CAS號(hào) | 154765-05-6 |
| 分子式 | C31H39FN6O2 |
| 分子量 | 546.6787632 |
| EINECS號(hào) | |
| 相關(guān)類別 | 多肽;Peptide |
| Mol文件 | 154765-05-6.mol |
| 結(jié)構(gòu)式 |  |
ADRENOMEDULLIN (13-52) (HUMAN) 性質(zhì)
| 儲(chǔ)存條件 | -15°C |
|---|---|
| 形態(tài) | 固體 |
| 顏色 | 白色至米白色 |
Adrenomedullin (AM) (13-52), human 是一種含 40 個(gè)氨基酸的多肽，可用作內(nèi)皮依賴性的血管舒張劑。
The effects of Adrenomedullin (AM) (13-52), human [hADM-(13-52)] are investigated in the rat pulmonary vascular bed and in isolated rings from the rat pulmonary artery (PA). Under conditions of controlled blood flow and constant left atrial pressure when tone is increased with U-46619, injection of hADM-(13-52) produces dose-related decreases in lobar arterial pressure. hADM-(13-52) modulates receptor-mediated, but not voltage-dependent, pulmonary vascular contraction by influencing Ca 2+ influx.