6H-PyriMido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-5,11-diMethyl- manufacturers
- ERK5-IN-1
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- $48.00 / 1mg
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2024-11-19
- CAS:1234479-76-5
- Min. Order:
- Purity: 99.42%
- Supply Ability: 10g
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| 6H-PyriMido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-5,11-diMethyl- Basic information |
Product Name: | 6H-PyriMido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-5,11-diMethyl- | Synonyms: | 6H-PyriMido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-5,11-diMethyl-;ERK5-IN-1;XMD 8-85;ERK5-IN-1 XMD 8-85;CS-2049;ERK5 inhibitor 1;2-((2-Methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-5,11-dimethyl-5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one;ERK5 IN 1,ERK,Inhibitor,ERK-5-IN-1,Extracellular signal regulated kinases,ERK5IN1,inhibit | CAS: | 1234479-76-5 | MF: | C25H29N7O2 | MW: | 459.54 | EINECS: | | Product Categories: | | Mol File: | 1234479-76-5.mol | |
| 6H-PyriMido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-5,11-diMethyl- Chemical Properties |
Melting point | >136°C (dec.) | Boiling point | 699.3±65.0 °C(Predicted) | density | 1.268±0.06 g/cm3(Predicted) | storage temp. | -20°C Freezer, Under inert atmosphere | solubility | Chloroform (Slightly), Methanol (Slightly) | form | Solid | pka | 7.75±0.42(Predicted) | color | Yellow to Dark Yellow |
| 6H-PyriMido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-5,11-diMethyl- Usage And Synthesis |
Uses | ERK5-IN-1 is a potent selective ERK5 inhibitor, inhibiting EGFR-induced ERK5 autophosphorylation and ERK5 enzymatic activity. Orally bioavailable. | Definition | ChEBI: 2-[2-methoxy-4-(4-methyl-1-piperazinyl)anilino]-5,11-dimethyl-6-pyrimido[4,5-b][1,4]benzodiazepinone is a member of piperazines. |
| 6H-PyriMido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-5,11-diMethyl- Preparation Products And Raw materials |
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