| Company Name: |
Suzhou Meishi Biotechnology Co., Ltd.
|
| Tel: |
1173954148q |
| Email: |
meishipharma@126.com |
| Products Intro: |
Product Name:346689-77-8
CAS:346689-77-8
Purity:99% HPLC Package:1G;5G;10G;100G;1KG;
|
| Company Name: |
Nantong QuanYi Biotechnology Co., Ltd
|
| Tel: |
0513-66337626 18051384581 |
| Email: |
sales@chemhifuture.com |
| Products Intro: |
Product Name:XR-11576
CAS:346689-77-8
Purity:98%+ HPLC Package:10mg，100mg，500mg，1g，2g，5g，10g，more
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:XR-11576
CAS:346689-77-8
Package:25mg/RMB 11700;100mg/RMB 19500;50mg/RMB 15300
|
Benzo[a]phenazine-11-carboxamide, N-[(1R)-2-(dimethylamino)-1-methylethyl]-4-methoxy- manufacturers
- XR-11576
-
- $1670.00 / 25mg
-
2024-10-28
- CAS:346689-77-8
- Min. Order:
- Purity:
- Supply Ability: 10g
|
| | Benzo[a]phenazine-11-carboxamide, N-[(1R)-2-(dimethylamino)-1-methylethyl]-4-methoxy- Basic information |
| | Benzo[a]phenazine-11-carboxamide, N-[(1R)-2-(dimethylamino)-1-methylethyl]-4-methoxy- Chemical Properties |
| Melting point | 116-118 °C | | Boiling point | 653.7±35.0 °C(Predicted) | | density | 1.228±0.06 g/cm3(Predicted) | | pka | 12.43±0.46(Predicted) |
| | Benzo[a]phenazine-11-carboxamide, N-[(1R)-2-(dimethylamino)-1-methylethyl]-4-methoxy- Usage And Synthesis |
| Uses | XR11576 (MLN576) is an orally active inhibitor of topoisomerase I and II. XR11576 shows cytotoxicity against human and murine tumor cell lines (IC50: 6-47 nM)[1]. | | References | [1] Di Nicolantonio F, et al. Ex vivo characterization of XR11576 (MLN576) against ovarian cancer and other solid tumors. Anticancer Drugs. 2004 Oct;15(9):849-60. DOI:10.1097/00001813-200410000-00005
[2] Mistry P, et al. In vitro and in vivo characterization of XR11576, a novel, orally active, dual inhibitor of topoisomerase I and II. Anticancer Drugs. 2002 Jan;13(1):15-28. DOI:10.1097/00001813-200201000-00002 |
| | Benzo[a]phenazine-11-carboxamide, N-[(1R)-2-(dimethylamino)-1-methylethyl]-4-methoxy- Preparation Products And Raw materials |
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