| Company Name: |
Shaanxi Xinyan Bomei Biotechnology Co., Ltd.
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| Tel: |
029-86217788 13892832556 |
| Email: |
2440688701@qq.com |
| Products Intro: |
Product Name:Mal-amido-PEG9-NHBoc
CAS:2182602-20-4
Purity:95% HPLC Package:1g;5g;10g;25g;100g;1kg
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| Company Name: |
Nanjing Shizhou Biology Technology Co.,Ltd
|
| Tel: |
025-85563444 18351873721 |
| Email: |
purchase@synzest.com |
| Products Intro: |
Product Name:Mal-amido-PEG9-NHBoc
CAS:2182602-20-4
Purity:95%HPLC Package:50mg;100mg;250mg;1g
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| | Mal-amido-PEG9-NHBoc Basic information |
| Product Name: | Mal-amido-PEG9-NHBoc | | Synonyms: | Mal-amido-PEG9-NHBoc;5,8,11,14,17,20,23,26,29-Nonaoxa-2,32-diazapentatriacontanoic acid, 35-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-33-oxo-, 1,1-dimethylethyl ester | | CAS: | 2182602-20-4 | | MF: | C32H57N3O14 | | MW: | 707.81 | | EINECS: | | | Product Categories: | | | Mol File: | 2182602-20-4.mol |  |
| | Mal-amido-PEG9-NHBoc Chemical Properties |
| Boiling point | 788.1±60.0 °C(Predicted) | | density | 1.163±0.06 g/cm3(Predicted) | | solubility | Soluble in DMSO, DCM, DMF | | pka | 12.23±0.46(Predicted) |
| | Mal-amido-PEG9-NHBoc Usage And Synthesis |
| Description | Mal-amido-PEG9-NHBoc is a PEG linker containing a maleimide group and a Boc protected amine group. The hydrophilic PEG spacer increases solubility in aqueous media. The protected amine can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. | | Uses | Mal-amido-PEG9-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Mal-amido-PEG9-NHBoc Preparation Products And Raw materials |
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