H-VAL-PRO-PRO-OH
| 中文名稱 | H-VAL-PRO-PRO-OH |
|---|---|
| 中文同義詞 | 化合物H-VAL-PRO-PRO-OH;(2S)-1-[(2S)-1-[(2S)-2-AMINO-3-METHYLBUTANOYL]PYRROLIDINE-2-CARBONYL]PYRROLIDINE-2-CARBOXYLIC ACID;抑制劑三肽VPP |
| 英文名稱 | H-VAL-PRO-PRO-OH |
| 英文同義詞 | H-VAL-PRO-PRO-OH;(S)-1-((S)-1-((S)-2-AMino-3-Methylbutanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxylic acid;VPP Tripeptide;L-Proline, L-valyl-L-prolyl-;inhibit,Angiotensin Receptor,Inhibitor,H Val Pro Pro OH,HValProProOH |
| CAS號 | 58872-39-2 |
| 分子式 | C15H25N3O4 |
| 分子量 | 311.38 |
| EINECS號 | |
| 相關(guān)類別 | |
| Mol文件 | 58872-39-2.mol |
| 結(jié)構(gòu)式 |  |
H-VAL-PRO-PRO-OH 性質(zhì)
| 沸點 | 566.4±50.0 °C(Predicted) |
|---|---|
| 密度 | 1.274±0.06 g/cm3(Predicted) |
| 儲存條件 | 2-8°C |
| 溶解度 | 溶于二甲基亞砜 |
| 酸度系數(shù)(pKa) | 3.42±0.20(Predicted) |
| 形態(tài) | 固體 |
| 顏色 | 白色至米白色 |
H-Val-Pro-Pro-OH，是牛奶來源的脯氨酸肽衍生物，是血管緊張素 I 轉(zhuǎn)化酶 (ACE) 的抑制劑，其IC50 為 9 μM。
IC50: 9 μM (ACE).
H-Val-Pro-Pro-OH, a proline peptides derivative, could inhibit Angiotensin I converting enzyme (ACE), with an IC 50 of 9 μM. H-Val-Pro-Pro-OH could enhance insulin sensitivity and prevent insulin resistance in 3T3-F442A pre-adipocytes. H-Val-Pro-Pro-OH also has anti-hypertensive and anti-inflammatory functions. H-Val-Pro-Pro-OH further enhances the expression of glucose transporter 4 (GLUT4) in adipocytes and restores glucose uptake in TNF-treated adipocytes.
安全信息
| 更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
|---|---|---|---|---|---|
| 2025/02/08 | HY-114161 | H-Val-Pro-Pro-OH | 58872-39-2 | 5 mg | 350元 |
| 2025/02/08 | HY-114161 | H-Val-Pro-Pro-OH | 58872-39-2 | 10 mg | 550元 |