| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Metallo-β-lactamase-IN-3
CAS:128294-71-3
Package:50mg/RMB 13800;100mg/RMB 17500;25mg/RMB 10600
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Benzoic acid, 4-[(3-mercapto-1-oxopropyl)amino]- manufacturers
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| | Benzoic acid, 4-[(3-mercapto-1-oxopropyl)amino]- Basic information |
| | Benzoic acid, 4-[(3-mercapto-1-oxopropyl)amino]- Chemical Properties |
| Boiling point | 496.6±30.0 °C(Predicted) | | density | 1.360±0.06 g/cm3(Predicted) | | pka | 4.30±0.10(Predicted) |
| | Benzoic acid, 4-[(3-mercapto-1-oxopropyl)amino]- Usage And Synthesis |
| Uses | Metallo-β-lactamase-IN-3 (compound 35) is a potent metallo-β-lactamases (MBL) inhibitor. Metallo-β-lactamase-IN-3 shows high activity against VIM-1 and NDM-1, with IC50 of 0.6 and 1.0 μM, respectively. Metallo-β-lactamase-IN-3 does not show inhibition of IMP-7[1]. | | References | [1] Kaya C, et al. N-Aryl Mercaptopropionamides as Broad-Spectrum Inhibitors of Metallo-β-Lactamases. J Med Chem. 2022 Mar 10;65(5):3913-3922. DOI:10.1021/acs.jmedchem.1c01755 |
| | Benzoic acid, 4-[(3-mercapto-1-oxopropyl)amino]- Preparation Products And Raw materials |
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