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| Tetraisopropyl methylenediphosphonate Basic information |
| Tetraisopropyl methylenediphosphonate Chemical Properties |
Hazard Codes | Xi | Risk Statements | 41 | Safety Statements | 26-36-39 | WGK Germany | 3 | TSCA | Yes | HS Code | 29319090 |
| Tetraisopropyl methylenediphosphonate Usage And Synthesis |
Chemical Properties | Clear colorless to slightly yellow liquid | Uses | Tetraisopropyl methylenediphosphonate [T(iPr)MDP] forms a synergistic mixture with hydrogen dicarbollylcobaltate in nitrobenzene which was used in the extraction of europium and americium. It may be used in the synthesis of the following:
- tetraisopropyl ethenylidenebisphosphonate.
- tetraisopropyl 4-acetylthiobutane-1,1-diphosphonate
- tetraisopropyl 2-(3,5-bis(bromomethyl)phenyl)ethane-1,1-diphosphonate
| Uses | Tetraisopropyl Methylenediphosphonate is used in the preparation of E2-bisphosphonate conjugates as potential anti-osteoporosis agents. Also used in the preparation of AZT 5’-Triphosphate compounds which display inhibitory effects on HIV-1 reverse transcrpitase. | General Description | Tetraisopropyl methylenediphosphonate (IPCP) is a tetraisopropyl ester of methylenediphosphonic acid. It is an electroneutral ligand, reported to be synthesized from triisopropyl phosphate. Powder electron paramagnetic resonance (EPR) studies of tris complexes of Cu(II) complexes with IPCP has been analyzed. |
| Tetraisopropyl methylenediphosphonate Preparation Products And Raw materials |
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