Company Name: |
J & K SCIENTIFIC LTD.
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Tel: |
010-82848833 400-666-7788 |
Email: |
jkinfo@jkchemical.com |
Products Intro: |
Product Name:14(S)-Hydroxy Docosahexaenoic Acid CAS:119433-37-3 Package:100μg,250μg,50μg
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Company Name: |
Yichang Zhongyitai Trading Co., Ltd.
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Tel: |
0717-6449896 13886658719 |
Email: |
root@zhongyitai.com |
Products Intro: |
Product Name:14(S)-Hydroxy-4(Z),7(Z),10(Z),12(E),16(Z),19(Z)-Docosahexaenoic acid CAS:119433-37-3 Purity:98+% Package:100ug
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- 14(S)-HDHA
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- $2500.00 / 100mg
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2024-10-24
- CAS:119433-37-3
- Min. Order:
- Purity:
- Supply Ability: 10g
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| 14(S)-Hydroxy Docosahexaenoic Acid Basic information |
Product Name: | 14(S)-Hydroxy Docosahexaenoic Acid | Synonyms: | 14(S)-Hydroxy Docosahexaenoic Acid;14(S)-HDHA;ZNEBXONKCYFJAF-OUKOMXQNSA-N;4,7,10,12,16,19-Docosahexaenoic acid, 14-hydroxy-, (4Z,7Z,10Z,12E,14S,16Z,19Z)-;14(S)-hydroxy-4(Z),7(Z),10(Z),12(E),16(Z),19(Z)-docosahexaenoic acid;14(S) HDHA,14(S)HDHA;14(S)-HDoHE;14(S)-hydroxy Docosahexaenoic Acid/14(S)-HDHA in Ethanol | CAS: | 119433-37-3 | MF: | C22H32O3 | MW: | 344.49 | EINECS: | | Product Categories: | Pharmaceuticals, Intermediates & Fine Chemicals | Mol File: | 119433-37-3.mol | |
| 14(S)-Hydroxy Docosahexaenoic Acid Chemical Properties |
Boiling point | 510.0±50.0 °C(Predicted) | density | 0.995±0.06 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS (pH 7.2): 0.5 mg/ml | pka | 4.58±0.10(Predicted) |
| 14(S)-Hydroxy Docosahexaenoic Acid Usage And Synthesis |
Description | 14(S)-HDHA is an oxygenation product formed by 12-lipoxygenase (12-LO) or 15-LO processing of docosahexaenoic acid (DHA; ). It is a precursor to the pro-resolving mediator maresin 1 and has been found in peritoneal exudates isolated from a mouse model of zymosan-induced peritonitis. | Uses | Docosahexaenoic acid (DHA; ) is a nutritionally-derived ω-3 fatty acid that is abundant in the brain and the retina and is thought to be important in early development and for therapeutic approaches to inflammatory disorders and cancer. 14(S)-HDHA is an oxygenation product of DHA that serves as a precursor to maresin 1 , an anti-inflammatory, pro-resolving mediator that prevents polymorphonuclear neutrophil (PMN) infiltration and stimulates macrophage phagocytosis. At doses as low as 0.2 ng/mouse 14(S)-HDHA administration resulted in reduced infiltration of PMNs into sites of inflammation.[Cayman Chemical] | Uses | 14(S)-Hydroxy Docosahexaenoic Acid is formed by human platelets. 14(S)-Hydroxy Docosahexaenoic Acid reacts with activated macrophages to form dihydroxy-containg products which posses potent antiinflammatory and proresolving activity. | Definition | ChEBI: (14S)-HDoHE is a 14-HDoHE in which the stereocentre at position 14 has S-configuration. It is a conjugate acid of a (14S)-HDoHE(1-). It is an enantiomer of a (14R)-HDoHE. |
| 14(S)-Hydroxy Docosahexaenoic Acid Preparation Products And Raw materials |
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