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125-65-5 Basic information More..
Product Name:Pleuromulin
Synonyms:PLEUROMULIN;PLEUROMUTILIN;a4014c;antibioticbc757;bc757;drosopholinb;glycolicacid,8-esterwithoctahydro-5,8-dihydroxy-4,6,9,10-tetramethyl-6-viny;l-3a,9-propano-3ah-cyclopentacycloocten-1(4h)-one
CAS:125-65-5
MF:C22H34O5
MW:378.5
EINECS:204-747-5
Mol File:125-65-5.mol
125-65-5

Use

Pleuromulin is Crystalline Solid Pleuromutilin is a diterpene produced by several species of basidomycete, notably the genus Pleurotus, discovered in 1951. Pleuromutilin is a potent and highly selective antibiotic active against a range of Gram positive bacteria, with no cross resistance to existing antibiotic classes due to its unique mode of action. Pleuromutilin inhibits protein synthesis by binding to domain V of 23S rRNA and this has led to the development of many semi-synthetic analogues as new generation antibiotics, such as tiamulin and retapamulin. Pleuromutilins such as tiamulin and valnemulin have been used for some time in veterinary medicine to treat swine infections. More recently a semisynthetic pleuromutilin, retapamulin, has been introduced as a topical treatment for Gram-positive infections in humans. Pleuromutilins inhibit the peptidyl transferase activity of the bacterial 50S ribosomal subunit by binding to the A site.

Pleuromulin manufacturers

  • Pleuromutilin
  • US $75.00-54.00 / mg
  • 2025-05-02
  • CAS:125-65-5
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  • Purity: 99.34%
  • Supply Ability: 10g
  • Pleuromulin
  • US $30.00 / kg
  • 2025-04-28
  • CAS:125-65-5
  • Min. Order: 1kg
  • Purity: 0.99
  • Supply Ability: 100 tons
  • Pleuromulin
  • US $10.00 / KG
  • 2025-04-23
  • CAS:125-65-5
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 10 mt
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