| | 19553-26-5 Basic information More.. |
| Product Name: | Cyclopenin | | Synonyms: | )-Isocyclopenin;)-Isocyclopenine;Spiro[3H-1,4-benzodiazepine-3,2'-oxirane]-2,5(1H,4H)-dione, 4-methyl-3'-phenyl-, (2'R,3'R)-rel-;rel-Isocyclopenine;Cyclopenin, AChE inhibitor;(±)-Cyclopenin | | CAS: | 19553-26-5 | | MF: | C17H14N2O3 | | MW: | 294.3 | | EINECS: | | | Mol File: | 19553-26-5.mol |  |
Use
Cyclopenin is one of an unusual family of benzodiazepine metabolites produced by a number of Penicillium species. Often mistakenly referred to as a mycotoxin, cyclopenin shows little toxicity against mammalian cells, bacteria or fungi in vitro. Cyclopenin is an intermediate in the biosynthesis of 3-O-methyl viridicatin, a strong inhibitor of TNFα-induced replication HIV. Lack of availability has hitherto restricted a more intensive investigation of this interesting metabolite.
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19553-26-5
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